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RNA Editing Uridylyltransferases of Trypanosomatids
2007Terminal RNA uridylyltransferases (TUTases) catalyze the transfer of UMP residues to the 3' hydroxyl group of RNA. These enzymes belong to the DNA polymerase beta superfamily, which also includes poly(A) polymerases, CCA-adding enzymes, and other nucleotidyltransferases.
Ruslan Aphasizhev, Inna Aphasizheva
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Proteome Diversification by RNA Editing
2020RNA editing is an RNA modification that alters the RNA sequence relative to its genomic blueprint. The most common type of RNA editing is A-to-I editing by double-stranded RNA-specific adenosine deaminase (ADAR) enzymes. Editing of a protein-coding region within the RNA molecule may result in non-synonymous substitutions, leading to a modified protein ...
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The evolution of edited RNA transcripts
Science, 2017RNA Editing Differences occur between nucleotides encoded within DNA and the RNAs transcribed from these sequences. Such RNA editing can lead to changes in the amino acid composition of resulting proteins, and the removal of editing can have pathological consequences. Examining the occurrence of A-to-I editing in coding and noncoding RNA transcripts in
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2008
RNA editing has been observed in chloroplast transcripts from most land plants, but not from algae. In higher plant chloroplasts, C-to-U conversion occurs at around 30 specific sites in mRNAs, many of which result in amino acid alteration. Occasionally, RNA editing creates an AUG initiation codon from ACG, and a UAA termination codon from CAA.
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RNA editing has been observed in chloroplast transcripts from most land plants, but not from algae. In higher plant chloroplasts, C-to-U conversion occurs at around 30 specific sites in mRNAs, many of which result in amino acid alteration. Occasionally, RNA editing creates an AUG initiation codon from ACG, and a UAA termination codon from CAA.
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A-to-I RNA editing — immune protector and transcriptome diversifier
Nature reviews genetics, 2018E. Eisenberg, E. Levanon
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RNA Editing with CRISPR Cas-13
Academia Letters, 2021Thualfeqar Almohanna
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Investigating RNA editing in deep transcriptome datasets with REDItools and REDIportal
Nature Protocols, 2020Claudio Lo Giudice +3 more
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Base editing: advances and therapeutic opportunities
Nature Reviews Drug Discovery, 2020Alexis C Komor, Gene W Yeo, Rui Kang
exaly
Spatiotemporal Delivery of CRISPR/Cas9 Genome Editing Machinery Using Stimuli‐Responsive Vehicles
Angewandte Chemie - International Edition, 2021Lanqun Mao, Ming Wang
exaly