Results 381 to 390 of about 2,110,017 (419)
Some of the next articles are maybe not open access.
CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo
Nature Biotechnology, 2022Philipp Reautschnig +12 more
semanticscholar +1 more source
Visualizing Nuclear RNA Editing
Trends in Biochemical Sciences, 2017RNA editing results in the site-specific conversion of adenosine to inosine in mRNAs. Genomics has revealed millions of editing sites in metazoans, but examining the spatial aspects of editing in cells has been challenging. A new method, inosineFISH (inoFISH), provides the ability to detect edited and unedited mRNAs within intact cells.
Hodaya Hochberg, Yaron Shav-Tal
openaire +3 more sources
RNA Editing Uridylyltransferases of Trypanosomatids
2007Terminal RNA uridylyltransferases (TUTases) catalyze the transfer of UMP residues to the 3' hydroxyl group of RNA. These enzymes belong to the DNA polymerase beta superfamily, which also includes poly(A) polymerases, CCA-adding enzymes, and other nucleotidyltransferases.
Ruslan Aphasizhev, Inna Aphasizheva
openaire +3 more sources
Proteome Diversification by RNA Editing
2020RNA editing is an RNA modification that alters the RNA sequence relative to its genomic blueprint. The most common type of RNA editing is A-to-I editing by double-stranded RNA-specific adenosine deaminase (ADAR) enzymes. Editing of a protein-coding region within the RNA molecule may result in non-synonymous substitutions, leading to a modified protein ...
openaire +2 more sources
The evolution of edited RNA transcripts
Science, 2017RNA Editing Differences occur between nucleotides encoded within DNA and the RNAs transcribed from these sequences. Such RNA editing can lead to changes in the amino acid composition of resulting proteins, and the removal of editing can have pathological consequences. Examining the occurrence of A-to-I editing in coding and noncoding RNA transcripts in
openaire +3 more sources
2008
RNA editing has been observed in chloroplast transcripts from most land plants, but not from algae. In higher plant chloroplasts, C-to-U conversion occurs at around 30 specific sites in mRNAs, many of which result in amino acid alteration. Occasionally, RNA editing creates an AUG initiation codon from ACG, and a UAA termination codon from CAA.
openaire +2 more sources
RNA editing has been observed in chloroplast transcripts from most land plants, but not from algae. In higher plant chloroplasts, C-to-U conversion occurs at around 30 specific sites in mRNAs, many of which result in amino acid alteration. Occasionally, RNA editing creates an AUG initiation codon from ACG, and a UAA termination codon from CAA.
openaire +2 more sources
A-to-I RNA editing — immune protector and transcriptome diversifier
Nature reviews genetics, 2018E. Eisenberg, E. Levanon
semanticscholar +1 more source
Investigating RNA editing in deep transcriptome datasets with REDItools and REDIportal
Nature Protocols, 2020Claudio Lo Giudice +3 more
semanticscholar +1 more source
RNA Editing with CRISPR Cas-13
Academia Letters, 2021Thualfeqar Almohanna
semanticscholar +1 more source