Results 331 to 340 of about 1,353,045 (362)

Donor activation in the T4 RNA ligase reaction

Biochemistry, 1985
T4 RNA ligase catalyzes the adenylation of donor oligonucleotide substrates. These activated intermediates react with an acceptor oligonucleotide which results in phosphodiester bond formation and the concomitant release of AMP. Adenylation of the four common nucleoside 3',5'-bisphosphates as catalyzed by T4 RNA ligase in the absence of an acceptor ...
Erika Graeser, Larry W. McLaughlin, Norbert Piel   +2 more
openaire   +3 more sources

Use of a 2-5A analogue probe for detecting RNA ligase and RNA ligase substrates in mammalian cell extracts

Biochemical and Biophysical Research Communications, 1984
The compound ppp(A2'p)3A3'[32P]pCp is a commercially available radioactive analogue of the 2',5' oligoadenylate series ppp(A2'p)nA, n greater than or equal to 2, commonly referred to as 2-5A. It is used as a probe for measuring concentrations in competition radiobinding and radioimmune assays.
P. Jane Cayley, Walden K. Roberts, Ian M. Kerr   +2 more
openaire   +3 more sources

Pyrococcus RNA ligase

, 2021
Y. Goldgur, S. Shuman, A. Banerjee
semanticscholar   +1 more source

RNA ligase

Catalysis from A to Z, 2020

semanticscholar   +1 more source

The bacterial RNA ligase RtcB accelerates the repair process of fragmented rRNA upon releasing the antibiotic stress

Science China Life Sciences, 2019
Muhammad Ramzan Manwar, Changjun Shao, Xing Shi, Jian Wang, Qiang Lin, Y. Tong, Yu Kang, Jun Yu   +7 more
semanticscholar   +1 more source

[2] Using T4 RNA ligase with DNA substrates

1983
Publisher Summary T4 RNA ligase forms a 3´ → 5´ phosphodiester bond between the 3´-hydroxyl and the 5´-phosphate of an oligoribonucleotide with the concomitant cleavage of ATP to AMP and PP i . In addition to the intramolecular circularization activity, the enzyme also joins oligonucleotides in an intermolecular reaction.
Catherine A. Brennan, Alice E. Manthey, Richard I. Gumport   +2 more
openaire   +3 more sources

E3 ligase ligand chemistries: from building blocks to protein degraders

Chemical Society Reviews, 2022
Izidor Sosi, Aleša Bricelj, Christian Steinebach   +2 more
exaly  

On the mechanism of T4 RNA ligase

Journal of the American Chemical Society, 1981
Floyd R. Bryant, Stephen J. Benkovic
openaire   +2 more sources

E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points

Frontiers in Chemistry, 2021
Aleša Bricelj, Christian Steinebach, Michael Gütschow   +2 more
exaly  

Drug Action and Aminoacyl RNA Ligases

Molecular Pharmacology, 1966
W F, Wevers, R K, Ralph
openaire   +2 more sources