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Locality and Gaps in RNA Comparison
Journal of Computational Biology, 2007Locality is an important and well-studied notion in comparative analysis of biological sequences. Similarly, taking into account affine gap penalties when calculating biological sequence alignments is a well-accepted technique for obtaining better alignments.
Rolf Backofen +6 more
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RNA localization inXenopusoocytes
Seminars in Cell & Developmental Biology, 1997The transport and localization of mRNAs within Xenopus oocytes contributes to an asymmetry that determines axis formation in the embryo. Several mRNAs become localized along the animal-vegetal axis. The mitochondrial cloud, a specialized cytoplasmic compartment which contributes to the formation of germ plasm, and the endoplasmic reticulum play ...
, Schnapp, , Arn, , Deshler, , Highett
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Localization of RNA in the synaptinemal complex
Journal of Ultrastructure Research, 1971This paper deals with the staining of meiotic chromosomes of Helix aspersa spermatocytes and Allium jesdianum microsporocytes, according to Bernhard's method. The presence of positive staining was observed in zygotene axial cores, in the lateral elements of the synaptinemal complexes, and in the remains of these structures during diplotene.
Esponda, Pedro, Stockert, Juan Carlos
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Axes formation and RNA localization
Current Opinion in Genetics & Development, 2005Axes formation in flies and frogs largely depends on RNA localization pathways functioning in the oocytes. It is thought that motors moving along the cytoskeleton enable the selective transport of RNAs to different destinations during oocyte development.
Svetlana, Minakhina, Ruth, Steward
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Localized control of oxidized RNA
Journal of Cell Science, 2015The oxidation of biological molecules by reactive oxygen species can render them inactive or toxic. This includes the oxidation of RNA, which appears to underlie detrimental effects of oxidative stress, aging, and certain neurodegenerative diseases. Here we investigate the management of oxidized RNA in the chloroplast of the green alga Chlamydomonas ...
Yu, Zhan +5 more
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RNA localization feeds translation
Science, 2017RNAs of the protein synthesis machinery relocalize to enhance the response to ...
Imre, Gáspár, Anne, Ephrussi
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Neuronal RNA Localization and the Cytoskeleton
2001The ability of a neuronal process to grow and be properly directed depends upon the growth cone, whose shape and sensory capabilities are influenced by dynamic cytoskeletal filament systems. Microfilaments, which are composed of actin, can rapidly form bundles that affect filopodial protrusions, growth cone motility and process growth.
G J, Bassell, R H, Singer
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RNA Localization: Getting to the Top
Current Biology, 1994Localizing gurken mRNA dorsally in Drosophila oocytes seems to be the first step in dorsoventral polarity establishment. Gurken, which resembles TGF alpha, may signal directly to dorsal follicle cells through the receptor Top.
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LOCAL SEQUENCE-STRUCTURE MOTIFS IN RNA
Journal of Bioinformatics and Computational Biology, 2004Ribonuclic acid (RNA) enjoys increasing interest in molecular biology; despite this interest fundamental algorithms are lacking, e.g. for identifying local motifs. As proteins, RNA molecules have a distinctive structure. Therefore, in addition to sequence information, structure plays an important part in assessing the similarity of RNAs.
Backofen, Rolf, Will, Sebastian
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RNA Localization in Xenopus Oocytes
2001Because of the relatively large size of Xenopus oocytes (up to 1.4 mm in diameter by the end of stage VI), their ease of injection and manipulation, and their clearly defined animal-vegetal polarity, this system represents one of the most intensively studied systems for RNA localization.
K, Rand, J, Yisraeli
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