Results 101 to 110 of about 174,288 (316)

Identification and targeting of a pan-genotypic influenza A virus RNA structure that mediates packaging and disease [PDF]

, 2021
Rachel J. Hagey, Menashe Elazar, Siqi Tian, Edward A. Pham, Wipapat Kladwang, Lily Ben‐Avi, Khanh Cong Nguyen, Anming Xiong, Meirav Rabinovich, Steven Schaffert, Talia Avisar, Benjamin Fram, Ping Liu, Purvesh Khatri, Jeffery K. Taubenberger, Rhiju Das, Jeffrey S. Glenn   +16 more
openalex   +1 more source

RNA Control of HIV-1 Particle Size Polydispersity [PDF]

, 2014
HIV-1, an enveloped RNA virus, produces viral particles that are known to be much more heterogeneous in size than is typical of non-enveloped viruses. We present here a novel strategy to study HIV-1 Viral Like Particles (VLP) assembly by measuring the ...
Beck, Yvonne, Bernaud, Julien, Castelnovo, Martin, Danial, John, Faivre-Moskalenko, Cendrine, Iazykov, Maksym, Lourdin, Morgane, Muriaux, Delphine, Tartour, Kevin, Thomas, Audrey   +9 more
core   +7 more sources

Visualizing Viral RNA Packaging Signals in Action

Journal of Molecular Biology
Here we confirm, using genome-scale RNA fragments in assembly competition assays, that multiple sub-sites (Packaging Signals, PSs) across the 5' two-thirds of the gRNA of Satellite Tobacco Necrosis Virus-1 make sequence-specific contacts to the viral CPs helping to nucleate formation of its T = 1 virus-like particle (VLP).
Wroblewski, E., Patel, N., Javed, A., Mata, C.P., Chandler-Bostock, R., Nair, L.B.G., Ulamec, S.M., Clark, S., Phillips, S.E.V., Ranson, N.A., Twarock, R., Stockley, P.G.   +11 more
openaire   +3 more sources

Packaging in a yeast double-stranded RNA virus [PDF]

Journal of Virology, 1995
The yeast virus ScV-L1 has only two genes, cap and pol, which encode the capsid polypeptide and the viral polymerase, respectively. The second gene is translated only as a cap-pol fusion protein. This fusion protein is responsible for recognition of a specific small stem and loop region of the viral plus strands, of 19 to 31 bases in length, ensuring ...
W, Yao, K, Muqtadir, J A, Bruenn
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Protein P7 of the cystovirus φ6 is located at the three-fold axis of the unexpanded procapsid. [PDF]

PLoS ONE, 2012
The objective of this study was to determine the location of protein P7, the RNA packaging factor, in the procapsid of the φ6 cystovirus. A comparison of cryo-electron microscopy high-resolution single particle reconstructions of the φ6 complete ...
Garrett Katz, Hui Wei, Alexandra Alimova, Al Katz, David Gene Morgan, Paul Gottlieb   +5 more
doaj   +1 more source

Transcript profiling for early stages during embryo development in Scots pine [PDF]

, 2016
Background: Characterization of the expression and function of genes regulating embryo development in conifers is interesting from an evolutionary point of view.
Abrahamsson, Malin, Canovas, Francisco, Craven-Bartle, Blanca, Merino, Irene, Sterck, Lieven, von Arnold, Sara   +5 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural dynamics of retroviral genome and the packaging

Frontiers in Microbiology, 2011
Retroviruses can cause diseases such as AIDS, leukemia and tumors, but are also used as vectors for human gene therapy. All retroviruses, except foamy viruses, package two copies of unspliced genomic RNA into their progeny viruses.
Yasuyuki eMiyazaki, Ariko eMiyake, Masako eNomaguchi, Akio eAdachi   +3 more
doaj   +1 more source

In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus. [PDF]

, 2015
Viruses in the Reoviridae, like the triple-shelled human rotavirus and the single-shelled insect cytoplasmic polyhedrosis virus (CPV), all package a genome of segmented double-stranded RNAs (dsRNAs) inside the viral capsid and carry out endogenous ...
Chang, Winston, Ding, Ke, Sun, Jingchen, Yu, Xuekui, Zhang, Xing, Zhou, Z Hong   +5 more
core