Results 291 to 300 of about 174,288 (316)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication. [PDF]

FEMS Microbiol Rev
Jehad MA, Ali LM, Pillai VN, Prabhu SG, Mustafa F, Rizvi TA.   +5 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Current perspectives on alphavirus encapsidation, assembly and budding. [PDF]

Front Cell Infect Microbiol
Bhardwaj K, Ranjith-Kumar CT, Guchhait P, Vrati S.   +3 more
europepmc   +1 more source

Illustration of the variable 1D sequences but conserved 2D and 3D structures of different ncRNA nanostructures for tracking the evolution and origin of organisms. [PDF]

Noncoding RNA Res
Jin K, Bohmer M, Guo P.
europepmc   +1 more source

Mixed Messages: Dynamic and Compositional Heterogeneity of Nuclear Messenger Ribonucleoprotein (mRNP) Complexes. [PDF]

Wiley Interdiscip Rev RNA
Wechsler T, Asada R, Montpetit B.
europepmc   +1 more source

Asymmetric isopeptide bond steers directional genomic RNA egress from icosahedral virus. [PDF]

Sci Adv
Braet SM, Venkatakrishnan V, Ramesh R, Clawson MA, Laremore TN, Wong SM, Anand GS.   +6 more
europepmc   +1 more source

Synthetic nanoparticles for cell-type specific, spatially resolved miRNA loading and export in neural cells

Mignanelli M, Siano G, Iannone V, Scarlatti A, Orsini E, Maggi L, Rizzo M, Caiazza MC, Wade-Martins R, Salvetti A, Ghiloni G, Cremisi F, Cattaneo A, Primio CD.   +13 more
europepmc   +1 more source

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Packaging RNA drugs into extracellular vesicles

Nature Biomedical Engineering, 2020
The therapeutic dose of small interfering RNA can be reduced by endogenously expressing and packaging the RNA into extracellular vesicles through its integration with the backbone of a highly enriched pre-microRNA.
van Eijndhoven, Monique A J, Baglio, S Rubina, Pegtel, D Michiel   +2 more
openaire   +3 more sources

Packaged Heteroclite Subgenomic RNAs of PRRSV

2001
Porcine reproductive and respiratory syndrome virus (PRRSV) is a member of the Arteriviridae family of the Nidovirales (Meulenberg et al, 1993b; Nelsen et al., 1999). While the complete genomes of three PRRSV strains are known (Allende et al., 1999; Meulenberg et al., 1993; Nelsen et al., 1999), main questions remains to be elucidated concerning viral ...
S, Yuan, M P, Murtaugh, K S, Faaberg
openaire   +2 more sources