Results 321 to 330 of about 2,070,961 (352)

Engineering a streamlined virus-like particle for programmable tissue-specific gene delivery. [PDF]

Nat Commun
Han J, Bai H, Li F, Zhang Y, Zhou Q, Li W.   +5 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Double-stranded RNA virus replication and packaging.

Journal of Biological Chemistry, 1993
openaire   +3 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Cytoplasmic domain of CM2 is involved in the replication of influenza C virus. [PDF]

J Gen Virol
Shimotai Y, Sugawara K, Matsuzaki Y, Muraki Y, Sho R, Goto T, Hamamoto H, Hongo S.   +7 more
europepmc   +1 more source

Pseudovirus as an Emerging Reference Material in Molecular Diagnostics: Advancement and Perspective. [PDF]

Curr Issues Mol Biol
Zheng L, Xu S.
europepmc   +1 more source

Lentiviral Vectors: From Wild-Type Viruses to Efficient Multi-Functional Delivery Vectors. [PDF]

Int J Mol Sci
Arrasate A, Lopez-Robles C, Zuazo M, Banos-Mateos S, Martin C, Lamsfus-Calle A, Fertin MJ.   +6 more
europepmc   +1 more source

The Role of MicroRNA-Based Strategies in Optimizing Plant Biomass Composition for Bio-Based Packaging Materials. [PDF]

Plants (Basel)
Belkozhayev AM, Abaildayev A, Kossalbayev BD, Kerimkulova A, Kadirshe DK, Toleutay G.   +5 more
europepmc   +1 more source

Revolution in an RNA-packaging capsid [PDF]

Science, 2021
Directed Evolution Artificial nucleocapsid proteins, which could be analogous to those used by viruses to package their genomes, are a promising way to protect and deliver RNAs. Using an escalating challenge by nucleases, Tetter et al.
M. Funk
semanticscholar   +2 more sources