Results 211 to 220 of about 1,363,084 (305)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Chemical Biology 2025: Highlights From the Ch/Bi145 Course at Caltech. [PDF]

Chembiochem
Ashton-Rickardt GP, Chung DK, Corman SA, Gilbert MS, Green ZB, Hengartner ER, Hou J, Kang D, Konsler JK, Kuleshova ID, Kuo LH, Acosta NL, Lee C, Leem E, Lin EN, Lin Y, Liu H, Liu Q, Liu Y, Teixeira AM, Nikas EG, Nisoli V, Polsani N, Power CM, Qi L, Qiang A, Rohrer SP, Salah O, Shu RR, Smith CS, Zhang Y, Cerione CS, Farhi J, Morstein J.   +33 more
europepmc   +1 more source

Conditional production of RNA hairpins in mammalian cells.

, 2003
TocchiniValentini GP Conditional production of RNA hairpins in mammalian cells, Deidda G, Calandra P, Mannironi C   +3 more
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Enhanced through-bond energy transfer-based bioorthogonal probe enables catalytic-amplified and sensitive detection of microRNA-21 for clinical lung cancer diagnosis. [PDF]

Smart Mol
Li Y, Han F, Huang H, Zhou D, Long S, Sun W, Du J, Fan J, Ning J, Peng C, Peng X.   +10 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Multiomics Integration Reveals Coexpression Regulatory Networks in Osteoporosis and Osteosarcoma. [PDF]

Int J Genomics
Fu D, Li R, Wang B.
europepmc   +1 more source

Targeted sequencing of both DNA strands barcoded and captured individually by RNA probes to identify genome-wide ultra-rare mutations. [PDF]

Sci Rep, 2017
Wang Q, Wang X, Tang PS, O'leary GM, Zhang M.   +4 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Mapping subcellular microenvironments using oligonucleotide-directed proximity labeling.

Curr Opin Chem Biol
Schactler SA, Skiados NG, Gajendragadkar AA, DeLeon LE, Shechner DM.   +4 more
europepmc   +1 more source