Results 111 to 120 of about 1,213,585 (311)

Decoding the dual recognition mechanism of the glucocorticoid receptor for DNA and RNA: sequence versus shape. [PDF]

Sci Rep, 2023
Hörberg J, Reymer A.
europepmc   +1 more source

Ultrasensitive electrochemical genosensor for direct detection of specific RNA sequences derived from avian influenza viruses present in biological samples

, 2019
Kamila Malecka, Edyta Świętoń, Peter Verwilst, Anna Stachyra, Agnieszka Sirko, Wim Dehaen, Jerzy Radecki, Hanna Radecka   +7 more
openalex   +2 more sources

RNA Sequencing v1

This protocols describes methods for RNA sequencing in human induced pluripotent stem cells.
Dahlia Rohm, Joshua black, Sean R. McCutcheon, Alejandro Barrera, Shante berry, Daniel Morone, Xander Nuttle, Celine de Esch, Derek Tai, Michael Talkowski, Nahid Iglesias, Charles A. Gersbach   +11 more
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Current Developments in RNA Sequence Analysis

Bioinformatics and Biology Insights, 2015
Jianping Zhang, Shaolei Teng, Cuncong Zhong, Bo Wang, Jie Wu   +4 more
doaj   +1 more source

Local changes in viral RNA sequence drive global changes in influenza nucleoprotein binding. [PDF]

J Med Virol, 2023
Le Sage V, Kanarek JP, Lakdawala SS, Lee N.   +3 more
europepmc   +1 more source

Short oligonucleotides as external guide sequences for site-specific cleavage of RNA molecules with human RNase P

, 1998
Martina Werner, Eddie Rosa, Jeffrey L. Nordstrom, Allan R. Goldberg, Shaji T. George   +4 more
openalex   +1 more source

Comparison of the Amplicor HIV-1 monitor test and the nucleic acid sequence-based amplification assay for quantitation of human immunodeficiency virus RNA in plasma, serum, and plasma subjected to freeze-thaw cycles [PDF]

, 1997
Brigitte P. Griffith, Michael O. Rigsby, Robin Garner, Mónica Gordón, T M Chacko   +4 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source