Results 271 to 280 of about 1,673,511 (373)

The NS4A Protein of Classical Swine Fever Virus Suppresses RNA Silencing in Mammalian Cells. [PDF]

J Virol, 2022
Qian Q, Xu R, Wang Y, Ma L.
europepmc   +1 more source

Role for Plasma Membrane-Related Ca2+-ATPase-1 (ATP2C1) in Pancreatic β-Cell Ca2+ Homeostasis Revealed by RNA Silencing [PDF]

, 2004
Kathryn J. Mitchell, Takashi Tsuboi, Guy A. Rutter   +2 more
openalex   +1 more source

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

Advanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo, Jiechun Lin, Qiwen Ren, Hao Sun, Yanhua Wu, Haofei Ge, Xiaolan Wu, Lihui Lin, Lining Liang, Changpeng Li, He Liu, Yuangbang Mai, Shilong Chu, Jiadong Liu, Jing Liu, Jiekai Chen, Duanqing Pei, Hui Zheng   +17 more
wiley   +1 more source

Straightforward and affordable agroinfiltration with RUBY accelerates RNA silencing research. [PDF]

Plant Mol Biol
Tabara M, Matsumoto A, Kibayashi Y, Takeda A, Motomura K.   +4 more
europepmc   +1 more source

Double transfection improves small interfering RNA‐induced thrombin receptor (PAR‐1) gene silencing in DU 145 prostate cancer cells [PDF]

, 2004
Jian Liu, P. Schuff‐Werner, Michael Steiner   +2 more
openalex   +1 more source

The role of PACT in the RNA silencing pathway

EMBO Journal, 2006
Yoontae Lee, Inha Hur, Seong-Yeon Park, Young‐Kook Kim, M. Suh, V. Kim   +5 more
semanticscholar   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

P25 and P37 proteins encoded by firespike leafroll-associated virus are viral suppressors of RNA silencing. [PDF]

Front Microbiol, 2022
Wang Y, Liu H, Wang Z, Guo Y, Hu T, Zhou X.   +5 more
europepmc   +1 more source

Silencing Expression of the Clusterin/Apolipoprotein J Gene in Human Cancer Cells Using Small Interfering RNA Induces Spontaneous Apoptosis, Reduced Growth Ability, and Cell Sensitization to Genotoxic and Oxidative Stress [PDF]

, 2004
Ioannis P. Trougakos, Alan So, Burkhard Jansen, Martin Gleave, Efstathios S. Gonos   +4 more
openalex   +1 more source

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

Advanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao, Yijia Yin, Fangyuan Shuai, Waishan Lam, Tao Zhou, Yaxin Xie, Xuesong He, Xianglong Han   +7 more
wiley   +1 more source