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Respective contributions of Arabidopsis DCL2 and DCL4 to RNA silencing.
The Plant Journal, 2015Dicer proteins are central to the different mechanisms involving RNA interference. Plants have evolved multiple DICER-LIKE (DCL) copies, thus enabling functional diversification.
Jean-Sébastien Parent+3 more
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Abstract The notion that the introduction of alien RNA into an organism can cause the silencing of endogenous genes and transgenes came to light in plants during the last decades of the 20th century. It was based on revealing virus-induced gene silencing (VIGS) and on the protection against pathogenic viruses by pre-infection with less pathogenic plant
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RNA Silencing in the Aspergilli
2007CONTENTS 13.1 Introduction 197 13.2 Experimental RNA Silencing 19813.2.1 Aspergillus fumigatus 198 13.2.2 Aspergillus fl avus and Aspergillus parasiticus 198 13.2.3 Experimental RNA Silencing During Infection 19913.3 Genetic Analysis of Experimental RNA Silencing 199 13.3.1 Aspergillus nidulans RNA Silencing Model 199 13.3.2
Nancy P. Keller, Thomas M. Hammond
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Science, 2001
In diverse organisms, small RNAs derived from cleavage of double-stranded RNA can trigger epigenetic gene silencing in the cytoplasm and at the genome level. Small RNAs can guide posttranscriptional degradation of complementary messenger RNAs and, in plants, transcriptional gene silencing by methylation of homologous DNA sequences.
Jan M. Kooter+2 more
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In diverse organisms, small RNAs derived from cleavage of double-stranded RNA can trigger epigenetic gene silencing in the cytoplasm and at the genome level. Small RNAs can guide posttranscriptional degradation of complementary messenger RNAs and, in plants, transcriptional gene silencing by methylation of homologous DNA sequences.
Jan M. Kooter+2 more
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RNA silencing and genome regulation
Trends in Cell Biology, 2005Closely related RNA silencing phenomena such as posttranscriptional and transcriptional gene silencing (PTGS and TGS), quelling and RNA interference (RNAi) represent different forms of a conserved ancestral process. The biological relevance of these RNA-directed mechanisms of silencing in gene regulation, genome defence and chromosomal structure is ...
Robin C. Allshire, Ricardo Almeida
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Science, 2000
Eukaryotic cells have developed an elegant system called RNA silencing for getting rid of foreign RNAs whether they be of viral, retrotransposon, or transgene origin. In his Perspective, [Baulcombe][1] examines new findings ([ Wu-Scharf et al .][2]) showing that in a green alga the gene responsible for RNA silencing encodes an RNA helicase (related to ...
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Eukaryotic cells have developed an elegant system called RNA silencing for getting rid of foreign RNAs whether they be of viral, retrotransposon, or transgene origin. In his Perspective, [Baulcombe][1] examines new findings ([ Wu-Scharf et al .][2]) showing that in a green alga the gene responsible for RNA silencing encodes an RNA helicase (related to ...
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2010
RNA silencing-related mechanisms have been documented in almost all living organisms and RNA silencing is now used as board term to describe the vast array of related processes involving RNA–RNA, RNA–DNA, RNA–protein or protein–protein interactions that ultimately result in the repression of gene expression.
Eamens, Andrew+2 more
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RNA silencing-related mechanisms have been documented in almost all living organisms and RNA silencing is now used as board term to describe the vast array of related processes involving RNA–RNA, RNA–DNA, RNA–protein or protein–protein interactions that ultimately result in the repression of gene expression.
Eamens, Andrew+2 more
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Frontiers in Biology, 2010
RNA silencing is an evolutionarily conserved mechanism in eukaryotic organisms induced by double-stranded RNA (dsRNA) and plays an essential role in regulating gene expression and maintaining genome stability. RNA silencing occurs at both posttranscriptional levels through sequence-specific RNA degradation or translational repression and at ...
Kemal Kazan+3 more
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RNA silencing is an evolutionarily conserved mechanism in eukaryotic organisms induced by double-stranded RNA (dsRNA) and plays an essential role in regulating gene expression and maintaining genome stability. RNA silencing occurs at both posttranscriptional levels through sequence-specific RNA degradation or translational repression and at ...
Kemal Kazan+3 more
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Viral suppressors of RNA silencing
Trends in Plant Science, 2011The infection and replication of viruses in the host induce diverse mechanisms for combating viral infection. One of the best-studied antiviral defence mechanisms is based on RNA silencing. Consistently, several viral suppressors of RNA silencing (VSRs) have been identified from almost all plant virus genera, which are surprisingly diverse within and ...
József Burgyán, Zoltán Havelda
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Viral suppressors of RNA silencing
Current Opinion in Biotechnology, 2001The suppression of RNA silencing by plant viruses represents a viral adaptation to a novel host antiviral defense. Three types of viral suppressors have been identified through the use of a variety of silencing suppression assays. The first two types of suppressor are capable of a complete or partial reversal of pre-existing RNA silencing; the third ...
Wan Xiang Li, Shou-Wei Ding
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