Results 251 to 260 of about 4,719,315 (357)

Liver Transcriptome Dynamics During Hibernation Are Shaped by a Shifting Balance Between Transcription and RNA Stability. [PDF]

Front Physiol, 2021
Gillen AE, Fu R, Riemondy KA, Jager J, Fang B, Lazar MA, Martin SL.   +6 more
europepmc   +1 more source

A test of the model to predict unusually stable RNA hairpin loop stability [PDF]

, 2000
Taraka Dale, RASHAAN SMITH, Martin J. Serra   +2 more
openalex   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

METTL16 inhibits pancreatic cancer proliferation and metastasis by promoting MROH8 RNA stability and inhibiting CAPN2 expression - experimental studies. [PDF]

Int J Surg
Yi T, Wang C, Ye X, Lin J, Lin C, Qin F, Yang W, Ye Y, Ning D, Lan J, Li H, Luo C, Ma J, Wei Z.   +13 more
europepmc   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

PARN Maintains RNA Stability to Regulate Insulin Maturation and GSIS in Pancreatic β Cells. [PDF]

Adv Sci (Weinh)
Xie X, Chen X, Wang C, Sun L, Yu W, Lv Z, Tian S, Yao X, Wang F, Ding D, Chen J, Liu J.   +11 more
europepmc   +1 more source

Stability of the mitochondrial genome requires an amino-terminal domain of yeast mitochondrial RNA polymerase

, 1999
Yuanhong Wang, Gerald S. Shadel
openalex   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Increased transcriptional elongation and RNA stability of GPCR ligand binding genes unveiled via RNA polymerase II degradation. [PDF]

Nucleic Acids Res
Bao L, Zhu J, Shi T, Jiang Y, Li B, Huang J, Ji X.   +6 more
europepmc   +1 more source