Results 121 to 130 of about 447,697 (355)
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
Interferon-lambda: A potent regulator of intestinal viral infections [PDF]
, 2017 Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and ...
Baldridge, Megan T, Lee, Sanghyun
core +3 more sources
FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions [PDF]
, 1985 We have obtained a vaccinia virus recombinant which contains a complete cDNA copy of the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome.
Franke, Christine A. +3 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective People with HIV (PWH) on antiretroviral therapy (ART) still experience neurocognitive dysfunction and accelerated brain volume loss. To assess whether the serotonergic and dopaminergic systems are affected, we used [11C]DASB positron emission tomography (PET) to assess presynaptic serotonergic function and [18F]FDOPA PET to measure ...
Chuen‐Yen Lau +12 more
wiley +1 more source
Analysis of an initial value problem for an extracellular and intracellular model of hepatitis C virus infection [PDF]
arXiv, 2020 In this paper, a mathematical analysis of the global dynamics of a viral infection model in vivo is carried out. We study the dynamics of a hepatitis C virus (HCV) model, under therapy, that considers both extracellular and intracellular levels of infection.
arxiv
Computer-designed orthogonal RNA aptamers programmed to recognize Ebola virus glycoproteins
Biosafety and Health, 2019 Ebola virus (EBOV), a member of the filovirus family, is an enveloped negative-sense RNA virus that causes lethal infections in humans and primates.
Yue Teng +6 more
doaj
Food Chemistry Advances, 2023 Background: The main threat to human health is infectious disease. For the treatment of infections with RNA viruses, there are hardly any antiviral drugs in the market.
Gajala Deethamvali Ghouse Peer +4 more
doaj
New Kids on the Block: RNA-Based Influenza Virus Vaccines
Vaccines, 2018 RNA-based immunization strategies have emerged as promising alternatives to conventional vaccine approaches. A substantial body of published work demonstrates that RNA vaccines can elicit potent, protective immune responses against various pathogens ...
Francesco Berlanda Scorza, Norbert Pardi
doaj +1 more source
HCV epidemiology in high-risk groups and the risk of reinfection [PDF]
, 2016 Injecting risk behaviours among people who inject drugs (PWID) and high-risk sexual practices among men who have sex with men (MSM) are important routes of hepatitis C virus (HCV) transmission.
Dalgard, Olav +6 more
core +2 more sources