Results 151 to 160 of about 447,697 (355)

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

open access: yesAdvanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling   +4 more
wiley   +1 more source

Assessing Concordance between RNA-Seq and NanoString Technologies in Ebola-Infected Nonhuman Primates Using Machine Learning [PDF]

open access: yesarXiv
This study evaluates the concordance between RNA sequencing (RNA-Seq) and NanoString technologies for gene expression analysis in non-human primates (NHPs) infected with Ebola virus (EBOV). We performed a detailed comparison of both platforms, demonstrating a strong correlation between them, with Spearman coefficients for 56 out of 62 samples ranging ...
arxiv  

Replication at periodically changing multiplicity of infection promotes stable coexistence of competing viral populations [PDF]

open access: yesEvolution 58:900-905, 2004, 2004
RNA viruses are a widely used tool to study evolution experimentally. Many standard protocols of virus propagation and competition are done at nominally low multiplicity of infection (m.o.i.), but lead during one passage to two or more rounds of infection, of which the later ones are at high m.o.i.
arxiv  

Quantitative estimation of Nipah virus replication kinetics in vitro

open access: yesVirology Journal, 2006
Background Nipah virus is a zoonotic virus isolated from an outbreak in Malaysia in 1998. The virus causes infections in humans, pigs, and several other domestic animals. It has also been isolated from fruit bats.
Hassan Sharifah   +3 more
doaj   +1 more source

Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou   +4 more
wiley   +1 more source

Methods of Repairing Virus Infected Files, A TRIZ based Analysis [PDF]

open access: yesarXiv, 2013
Most viruses are capable of fixing up the first few bytes and repair the original program because they have to return the control back to the infected program. This fact is used by a heuristic cleaner to clean the infected file. As the virus knows how to repair the it uses the same virus to repair the infected file.
arxiv  

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