New Perspectives on the Biogenesis of Viral Inclusion Bodies in Negative-Sense RNA Virus Infections. [PDF]
Dolnik O, Gerresheim GK, Biedenkopf N.
europepmc +1 more source
Abortive infection of L cells by influenza virus: absence of virion RNA synthesis [PDF]
R. J. Avery
openalex +1 more source
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling+4 more
wiley +1 more source
Assessing Concordance between RNA-Seq and NanoString Technologies in Ebola-Infected Nonhuman Primates Using Machine Learning [PDF]
This study evaluates the concordance between RNA sequencing (RNA-Seq) and NanoString technologies for gene expression analysis in non-human primates (NHPs) infected with Ebola virus (EBOV). We performed a detailed comparison of both platforms, demonstrating a strong correlation between them, with Spearman coefficients for 56 out of 62 samples ranging ...
arxiv
Replication at periodically changing multiplicity of infection promotes stable coexistence of competing viral populations [PDF]
RNA viruses are a widely used tool to study evolution experimentally. Many standard protocols of virus propagation and competition are done at nominally low multiplicity of infection (m.o.i.), but lead during one passage to two or more rounds of infection, of which the later ones are at high m.o.i.
arxiv
Quantitative estimation of Nipah virus replication kinetics
Background Nipah virus is a zoonotic virus isolated from an outbreak in Malaysia in 1998. The virus causes infections in humans, pigs, and several other domestic animals. It has also been isolated from fruit bats.
Hassan Sharifah+3 more
doaj +1 more source
Formation and Function of Liquid-Like Viral Factories in Negative-Sense Single-Stranded RNA Virus Infections. [PDF]
Su JM, Wilson MZ, Samuel CE, Ma D.
europepmc +1 more source
Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou+4 more
wiley +1 more source
Methods of Repairing Virus Infected Files, A TRIZ based Analysis [PDF]
Most viruses are capable of fixing up the first few bytes and repair the original program because they have to return the control back to the infected program. This fact is used by a heuristic cleaner to clean the infected file. As the virus knows how to repair the it uses the same virus to repair the infected file.
arxiv
Detection of DNA and RNA virus genomes in organ systems of whole mice: patterns of mouse organ infection by polyomavirus [PDF]
Thomas W. Dubensky+2 more
openalex +1 more source