Results 151 to 160 of about 605,647 (350)

Simian virus 40 small-t does not transactivate RNA polymerase II promoters in virus infections [PDF]

, 1991
Prithi Rajan, V Dhamankar, Kathleen Rundell, Bayar Thimmapaya   +3 more
openalex   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Development of a Novel Plasmid-based Eukaryotic Model to Investigate Crimean-Congo Hemorrhagic Fever Virus

Bezmiâlem Science
Objective: Crimean-Congo Hemorrhagic Fever (CCHF) is a severe tick-borne viral disease, caused by the Crimean-Congo Hemorrhagic Fever virus (CCHFV).
Nesibe Selma GÜLER ÇETİN, Özlem BAKANGİL, Merve KALKAN YAZICI, Sercan KESKİN, Mehmet Ziya DOYMAZ   +4 more
doaj   +1 more source

Clinical Correlates of Human Immunodeficiency Virus–1 (HIV-1) DNA and Inducible HIV-1 RNA Reservoirs in Peripheral Blood in Children With Perinatally Acquired HIV-1 Infection With Sustained Virologic Suppression for at Least 5 Years [PDF]

, 2019
Ari Bitnun, Doris G. Ransy, Jason Brophy, Fatima Kakkar, Michael Hawkes, Lindy Samson, Bayader Annabi, Amélie Pagliuzza, Jacob-Adams Morand, Laura Sauvé, Nicolas Chomont, Stephanie Lavoie, John Kim, Paul Sandstrom, Paul A. Wender, Terry Lee, Joel Singer, Stanley Read, Hugo Soudeyns, Ariane Alimenti, Petronela Ancuța, Bitnun Ari, Jason Brophy, Bullard Jared, Chun Tae-Wook, Cassoudesalle Hélène, Embree Joanne, T Hawkes Michael, Kakkar Fatima, Christos Karatzios, Rupert Kaul, J. Kim, Lamarre Valérie, Lapointe Normand, Pascal M. Lavoie, L Delovitch Terry, M. Money Deborah, M. Ryan Dorothy, Read Stanley, Robert Reinhard, Lindy Samson, Sandstorm Paul, Sauve Laura, S. Ojeda Sandra, Joel Singer, Hugo Soudeyns, Tan Ben, Vaudry Wendy   +47 more
openalex   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Selenium and RNA viruses interactions: Potential implications for SARS-CoV-2 infection (COVID-19)

, 2020
Laurent Hiffler
openalex   +1 more source

Inhibition of hepatitis C virus infection and expression in vitro and in vivo by recombinant adenovirus expressing short hairpin RNA [PDF]

, 2007
Naoya Sakamoto, Yoko Tanabe, Takanori Yokota, Kenichi Satoh, Yuko Sekine‐Osajima, Mina Nakagawa, Yasuhiro Itsui, Megumi Tasaka, Y. Sakurai, Chen Cheng‐Hsin, Masahiko Yano, Shogo Ohkoshi, Yutaka Aoyagi, Shinya Maekawa, Nobuyuki Enomoto, Michinori Kohara, Mamoru Watanabe   +16 more
openalex   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

hnRNPA2B1 recognizes RNA virus SFTSV infection through mitochondrial DNA

mBio
The heterogeneous nuclear ribonucleoprotein (hnRNPA2B1, hereafter A2B1) was identified as a novel nuclear DNA sensor that mediates antiviral immunity by recognizing viral DNA in the nucleus. However, it remains largely unclear whether A2B1 could function
Xin-bo Huang, Yue Zhang, Jing-wen Fan, Xin-yu Yu, Yun-lan Fang, Jin-xin Ren, Bin-yan Liu   +6 more
doaj   +1 more source