Results 161 to 170 of about 605,647 (350)

Nucleocytoplasmic shuttling of the West Nile virus RNA ‐dependent RNA polymerase NS5 is critical to infection [PDF]

, 2018
Adam J. López‐Denman, Alice Russo, Kylie M. Wagstaff, Peter A. White, David A. Jans, Jason M. Mackenzie   +5 more
openalex   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Favipiravir, an anti-influenza drug against life-threatening RNA virus infections. [PDF]

Pharmacol Ther, 2020
Shiraki K, Daikoku T.
europepmc   +1 more source

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. [PDF]

, 2006
A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness.
Blackburn, Brian G, Chiu, Charles Y, DeRisi, Joseph L, Eckburg, Paul B, Fischer, Kael, Ganem, Don, Koshy, Anita, Merker, Jason D, Patterson, Bruce K, Rouskin, Silvi, Schnurr, David, Tompkins, Lucy S, Urisman, Anatoly, Yagi, Shigeo   +13 more
core  

Corrigendum: Zika Virus Infection Results in Biochemical Changes Associated With RNA Editing, Inflammatory and Antiviral Responses in Aedes albopictus [PDF]

, 2021
Maria G. Onyango, Geoffrey M. Attardo, Erin Taylor Kelly, Sean Bialosuknia, Jessica L. Stout, Elyse Banker, Lili Kuo, Alexander T. Ciota, Laura D. Kramer   +8 more
openalex   +1 more source

Triazine‐Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Novel photo‐clickable triazine‐trione thermosets can be shaped and cured under mild conditions, including room and physiological temperatures. These materials are biocompatible and support osteogenic differentiation of bone marrow–derived mesenchymal stem cells on their surface.
Åshild Johansen, Shuntaro Yamada, Daniel J. Hutchinson, Mohammed A. Yassin, Samih Mohamed‐Ahmed, Cecilie Gjerde, Michael Malkoch, Kamal Mustafa   +7 more
wiley   +1 more source

Argonaute 2 targets viral transcripts but not genomes of RNA viruses during antiviral RNA interference in Drosophila.

PLoS Pathogens
RNA interference (RNAi) mediated by the small interfering RNA (siRNA) pathway is a major antiviral mechanism in insects. This pathway is triggered when double-stranded RNA (dsRNA) produced during virus replication is recognized by Dicer-2, leading to the
Emanuele G Silva, Isaque J S de Faria, Álvaro G A Ferreira, Thiago Henrique L Jiran, Carlos F Estevez-Castro, Juliana N Armache, Siad C G Amadou, Yann Verdier, Joëlle Vinh, Karim Majzoub, Carine Meignin, Gabrielle Haas, Franck Martin, Jean-Luc Imler, João T Marques   +14 more
doaj   +1 more source

Increasing hepatitis C virus RNA levels in hemophiliacs: relationship to human immunodeficiency virus infection and liver disease. Multicenter Hemophilia Cohort Study [PDF]

, 1994
M. Elaine Eyster, MW Fried, AM Di Bisceglie, J. J. Goedert   +3 more
openalex   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Single-cell RNA-seq revealed heterogeneous responses and functional differentiation of hemocytes against white spot syndrome virus infection in Litopenaeus vannamei [PDF]

Chuang Cui, Xiaoqian Tang, Jing Xing, Xiuzhen Sheng, Heng Chi, Wenbin Zhan   +5 more
openalex   +1 more source