Results 281 to 290 of about 447,697 (355)

Virus-specific RNA in Cells Productively Infected or Transformed by Polyoma Virus

Cold Spring Harbor Symposia on Quantitative Biology, 1974
D. M. Lindstrom, R. Kamen, H. Shure, R. W. Old   +3 more
openaire   +3 more sources

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

Advanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo, Jiechun Lin, Qiwen Ren, Hao Sun, Yanhua Wu, Haofei Ge, Xiaolan Wu, Lihui Lin, Lining Liang, Changpeng Li, He Liu, Yuangbang Mai, Shilong Chu, Jiadong Liu, Jing Liu, Jiekai Chen, Duanqing Pei, Hui Zheng   +17 more
wiley   +1 more source

Genomic changes of Lassa virus associated with mammalian host adaptation. [PDF]

BMC Genomics
Easterbrook L, Dong X, Smith J, Fotheringham S, Kempster S, Hartley C, Prince T, Graham V, Kennedy E, Findlay-Wilson S, Crossley L, Hewson R, Almond N, Hiscox JA, Dowall S.   +14 more
europepmc   +1 more source

Plasma RNA Viral Load in Human Immunodeficiency Virus Type 2 Subtype A and Subtype B Infections

, 2002
Florence Damond, Marie Gueudin, Sophie Pueyo, Isabelle Farfara, David L. Robertson, Diane Descamps, Geneviève Chêne, Sophie Matheron, Pauline Campa, Françoise Brun‐Vézinet, François Simon   +10 more
openalex   +1 more source

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

An inactivated influenza D virus vaccine protects guinea pigs from infections and contact transmission caused by homologous challenge. [PDF]

Virol J
Dong Z, Lu P, Feng Y, Gao H, Wan W, Wang T, Xia X, Sun W, Gao Y.   +8 more
europepmc   +1 more source

Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin

Advanced Science, EarlyView.
Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez, Michael P. Andreas, Tobias W. Giessen   +2 more
wiley   +1 more source

Can Adoptive Immunotherapy With Hepatitis E Virus (HEV)-Specific T Cells Address the Unmet Need in Refractory Chronic HEV Infection? [PDF]

Open Forum Infect Dis
Lampejo T.
europepmc   +1 more source

Targeting PTBP3‐Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis

Advanced Science, EarlyView.
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou, Chao Dong, Xiaochun Shen, Pengbo Wang, Tao Chen, Weikang Li, Xiaotong Sun, Peiyuan Li, Chengxiang Xu, Kaipeng Duan, Dongbao Li, Jin Zhou   +11 more
wiley   +1 more source

Prevalence and Diversity of Haemosporidian-Associated Matryoshka RNA Viruses in a Natural Population of Wild Birds. [PDF]

Ecol Evol
Esperanza CW, Faircloth CE, Roy SW, Sehgal RNM.   +3 more
europepmc   +1 more source