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INHIBITION OF CELL FUNCTIONS BY RNA-VIRUS INFECTIONS
Annual Review of Microbiology, 1984The studies with poliovirus have revealed that cells have a full capacity to translate uncapped mRNA, although their own mRNAs are capped and methylated. These observations have been confirmed by translation studies in fractionated systems in vitro.
L, Kääriäinen, M, Ranki
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Virus Infection Cycle Events Coupled to RNA Replication
Annual Review of Phytopathology, 2014Replication, the process by which the genetic material of a virus is copied to generate multiple progeny genomes, is the central part of the virus infection cycle. For an infection to be productive, it is essential that this process is coordinated with other aspects of the cycle, such as translation of the viral genome, encapsidation, and movement of ...
Pooja, Saxena, George P, Lomonossoff
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Nucleus-associated RNA in measles virus-infected cells
Biochemical and Biophysical Research Communications, 1973Abstract Measles virus RNA was found in the nuclear fraction of infected Vero cells. 24-hr labeling periods revealed heterogeneously sedimenting 15–50 S RNA associated with a membrane-containing particulate. Viral RNA isolated after shorter labeling periods was larger in size (30–50 S) and associated with both nucleoplasmic and particulate fractions.
C, Carter, F L, Black, A, Schluederberg
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Double-stranded RNA in Vaccinia Virus Infected Cells
Nature, 1969Double-stranded RNA has been isolated from chick cells and chick cells infected with vaccinia virus. The double-stranded vaccinia virus RNA induces production of interferon.
C, Colby, P H, Duesberg
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Paramyxovirus and other RNA virus infections
2021Chapter is based on the results of long-time (1970–2020) studies of A.V. and V.A. Zinserling and their collaborators on children and adult autopsy material in comparison with literary data and includes sections: parainfluenza, respiratory syncytial, metapneumovirus infection, and measles.
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Viral RNA synthesis in measles virus-infected cells
Virology, 1973Abstract Sedimentation analysis of measles virus-specific cytoplasmic RNA at different times after infection revealed several size classes. The three specific components found in greatest amount were estimated to have sedimentation coefficients of 20 S, 27 S, and 35 S. A fourth component, 52 S, sedimented with characteristics of viral RNA.
C, Carter, A, Schuluederberg, F L, Black
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RNA-RNA RECOMBINATION AND EVOLUTION IN VIRUS-INFECTED PLANTS
Annual Review of Phytopathology, 1994Viruses that depend on RNA-dependent RNA polymerases (RdRp) for repli cation of their genomic and subgenomic RNAs are subject to high inherent misincorporation of nucleotides that can lead to heterogeneous mixtures of related species (46, 93). It has been proposed that RNA viruses evolved the means for correcting high error rates through an ability to
A. E. Simon, J. J. Bujarski
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RNA Interference to Treat Virus Infections
2015In spite of its young age, the field of RNA interference has already yielded major advances in the laboratory. This sequence-specific mechanism of gene regulation also holds strong promise for the development of a new generation of drugs, in particular to control the everlasting threat of viral infections.
Karim Majzoub, Jean-Luc Imler
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Infectivity of partially encapsidated tobacco mosaic virus RNA
Virology, 1979Tobacco mosaic virus was reconstituted in vitro, and the infectivity of intermediate products at various stages of reconstitution was investigated in relation to their rod length. The infectivity of intermediates was exponentially related to their rod length throughout the reconstitution process, indicating that no particular region of TMV-RNA is ...
M, Fukuda +3 more
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Immunofluorescent demonstration of double-stranded RNA and virus antigen in RNA virus-infected cells
Virology, 1974Abstract The indirect immunofluorescence procedure has been used for demonstration of double-stranded RNA in cells infected with reovirus, poliomyelitis, and tick-borne encephalitis (TBE) viruses. Rabbit sera against poly(A)-poly(U) and poly(I)-poly(C) react specifically with double-stranded RNA.
I N, Gavrilovskaya +5 more
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