Results 291 to 300 of about 3,202,245 (403)
Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses
Bryan C. Mounce +23 more
semanticscholar +1 more source
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An +8 more
wiley +1 more source
The Role of Chemical Modifications in the Genome of Negative-Sense RNA Viruses on the Innate Immune Response. [PDF]
Ceballos MA, Acevedo ML.
europepmc +1 more source
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen +31 more
wiley +1 more source
Fighting RNA viruses with a gold nanoparticle Cas13d gene-editing armor. [PDF]
De Carli A +17 more
europepmc +1 more source
Positive-strand RNA viruses stimulate host phosphatidylcholine synthesis at viral replication sites
Jiantao Zhang +7 more
semanticscholar +1 more source
Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong +21 more
wiley +1 more source

