Results 331 to 340 of about 3,202,245 (403)

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Vaccine Strategies Against RNA Viruses: Current Advances and Future Directions. [PDF]

Vaccines (Basel)
Hsiung KC, Chiang HJ, Reinig S, Shih SR.
europepmc   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Viroid-like "obelisk" agents are widespread in the ocean and exceed the abundance of RNA viruses in the prokaryotic fraction. [PDF]

ISME J
López-Simón J, de la Peña M, Martínez-García M.   +2 more
europepmc   +1 more source

Diverse RNA viruses discovered in multiple seagrass species. [PDF]

PLoS One
Rede JE, Breitbart M, Lundquist C, Nagasaki K, Hewson I.   +4 more
europepmc   +1 more source

Analysis of the interaction between the helper component proteinase (HC-Pro) of Zucchini yellow mosaic virus (ZYMV) and the plant RNA methyltransferase Hua enhancer 1 (HEN1)

, 2012
Rana Jamoos
openalex   +1 more source

Metatranscriptomic identification of novel RNA viruses from raccoon dog (Nyctereutes procyonoides) feces in Japan. [PDF]

Sci Rep
Oba M, Sakaguchi S, Teshima N, Yokota T, Takemae H, Tohei M, Shimokawa F, Murakami M, Mizuno S, Ishida H, Murakami H, Takano T, Mizutani T, Tsukada H, Nagai M.   +14 more
europepmc   +1 more source

Metatranscriptomic analysis reveals the diversity of RNA viruses in ticks in Inner Mongolia, China. [PDF]

PLoS Negl Trop Dis
Su S, Cui MY, Xing LL, Gao RJ, Mu L, Hong M, Guo QQ, Ren H, Yu JF, Si XY, Eerde M.   +10 more
europepmc   +1 more source

Comparison of the S-RNA and M-RNA sequences of the parental and derived (resistance breaking) isolates of Tomato spotted wilt virus that defeat resistance gene Tsw

, 2006
FS Poke, Richard A. Jones, CR Wilson
openalex