Results 141 to 150 of about 13,181 (183)

Substrate Specificity Checkpoints of the Multidrug Efflux Pump MexF from <i>Pseudomonas aeruginosa</i>. [PDF]

ACS Infect Dis
Uddin MR, Gervasoni S, Malloci G, Ruggerone P, Zgurskaya HI.   +4 more
europepmc   +1 more source

Profiling Ten RHO GTPases in Myeloid Malignancies Reveals Distinct Expression Patterns and Prognostic Associations. [PDF]

Cancer Med
de Almeida Rodrigues B, de Paiva LB, Ramalho MCC, Damasceno AF, Saad STO, Lazarini M.   +5 more
europepmc   +1 more source

Characterization of RND efflux pumps of Serratia marcescens

, 2005
openaire   +1 more source

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Function and regulation of Rnd proteins

Nature Reviews Molecular Cell Biology, 2006
The Rnd proteins, which form a distinct sub-group of the Rho family of small GTP-binding proteins, have been shown to regulate the organization of the actin cytoskeleton in several tissues. In the brain, they participate in neurite extension, whereas in smooth muscle, they modulate contractility.
Chardin Pierre
exaly   +3 more sources

Computer simulations of the activity of RND efflux pumps

Research in Microbiology, 2018
The putative mechanism by which bacterial RND-type multidrug efflux pumps recognize and transport their substrates is a complex and fascinating enigma of structural biology. How a single protein can recognize a huge number of unrelated compounds and transport them through one or just a few mechanisms is an amazing feature not yet completely unveiled ...
Attilio V Vargiu, Venkata Krishnan Ramaswamy, Giuliano Malloci   +2 more
exaly   +5 more sources

The hydrophobic trap—the Achilles heel of RND efflux pumps [PDF]

Research in Microbiology, 2018
Resistance-nodulation-division (RND) superfamily efflux pumps play a major role in multidrug resistance (MDR) of Gram-negative pathogens by extruding diverse classes of antibiotics from the cell. There has been considerable interest in developing efflux pump inhibitors (EPIs) of RND pumps as adjunctive therapies.
Zachary D Aron, Timothy J Opperman
exaly   +3 more sources

A Census of RND Superfamily Proteins in the Burkholderia Genus

Future Microbiology, 2013
The aim of this work was to analyze the eight resistance-nodulation-cell division (RND) families (a group of proteins mainly involved in multidrug resistance of Gram-negative bacteria) in 26 Burkholderia genomes in order to gain knowledge regarding their presence and distribution, to obtain a platform for future experimental tests aimed to identify new
PERRIN, ELENA, FONDI, MARCO, PAPALEO, MARIA CRISTIANA, MAIDA, ISABEL, EMILIANI, GIOVANNI, S. Buroni, M. R. Pasca, G. Riccardi, FANI, RENATO   +8 more
openaire   +5 more sources