Results 91 to 100 of about 981,881 (296)
The Social Cost of Road Congestion in Ile-de-France Region (and France): Empirical Evidences from the Paris Ring-Road [PDF]
The aim of this article was to assess specific problems concerning traffic congestion access to the city of Paris. First, we attempted to evaluate the evolution of the congestion cost for the Paris Ring-Road (PRR), the major urban highway surrounding the
Martin Koning
core
An Agent Based Model for the Simulation of Transport Demand and Land Use [PDF]
, 2015 Agent based modelling has emerged as a promising tool to provide planners with insights on social behaviour and the interdependencies characterising urban system, particularly with respect to transport and infrastructure planning.
Barthelemy, J. +5 more
core
FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Built Environment Analysis for Road Traffic Crash Hotspots in Kigali, Rwanda
Frontiers in Sustainable Cities, 2020 Introduction: Road traffic injuries (RTIs) are a significant cause of morbidity and mortality in Rwanda. Investigations of the high risk areas for road traffic crashes (RTCs) are urgently needed to guide improvements in road safety.
Daphne Wang +10 more
doaj +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Spatial Analysis and Identification of Erosion and Sediment Hot-Spots Along Zagros Forest Roads [PDF]
علوم آب و خاکIn the present study, the Road Sediment Delivery Model (SEDMODL) and Geographic Information System (GIS) were utilized to estimate the average annual sedimentation caused by the forest road network in the oak forests in the west of Iran, Chaharmahal and ...
S. Yousefi +3 more
doaj
Do all roads lead to resistance? State road density is the main impediment to gene flow in a flagship species inhabiting a severely fragmented anthropogenic landscape. [PDF]
Ecol Evol, 2021 Westekemper K +5 more
europepmc +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source