Results 101 to 110 of about 1,173,182 (282)
Regional air quality and major sources can be reflected by dust. 87 dust samples in Nanchang (four residential areas and three roadside points) were collected, with particle size and carbon components determined to discuss the distribution ...
Hong Huang +6 more
doaj +1 more source
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt +16 more
wiley +1 more source
A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg +16 more
wiley +1 more source
copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department of Transport, Road Accident Statistics Branch
core +1 more source
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng +9 more
wiley +1 more source
copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department for Transport, Road Accident Statistics Branch
core +1 more source
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Quantification of tire tread wear particle in road dust through pyrolytic technique. [PDF]
Chae E, Choi SS.
europepmc +1 more source
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong +8 more
wiley +1 more source
copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department for Transport, Road Accident Statistics Branch
core +1 more source

