Results 31 to 40 of about 4,579 (254)

INTERMODAL TRANSPORT AND STANDARDISATION [PDF]

open access: yesFiabilitate şi Durabilitate, 2012
Almost gone unnoticed, a new era started in rail freight transport. Whereas the conventional “wagonload” rail freight transport stagnates, road-rail Combined Transport (CT) was able to register high growth rates.
Marcel LITRA, Stefan IOVAN
doaj  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

THE IMPACT OF INFORMATION AND COMMUNICATION TECHNOLOGY ON ROAD FREIGHT TRANSPORTATION

open access: yesIATSS Research, 2005
Surveying the recent trend toward e-commerce and computerization in the trucking industry, this paper establishes a framework for analyzing the impact of information and communication technology on road freight transportation in terms of commerce ...
Ryuichi YOSHIMOTO
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The use of freight apps in road freight transport for CO2 reduction [PDF]

open access: yesEuropean Transport Research Review, 2017
Abstract Purpose The purpose of this study was to investigate how a smart phone freight application service (Apps) could reduce CO2 emissions in road freight transport and to identify the core problems for improvements. Methods This research uses a multiple-case-study approach to examine several existing freight apps in the Chinese market.
Ye Li, Yuewu Yu
openaire   +2 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Evaluation of Threats Occurring During Provision of Road Transport Services in the EU Territory by Small and Medium-Sized Companies from Poland

open access: yesZeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej, 2020
The aim of the paper is to conduct an analysis of various threats that may occur during road freight transport in the territory of the European Union. The research method consisted of a survey and the sample group selected for the survey were transport ...
Marek Krzywonos
doaj   +10 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

An electric road system or big batteries: Implications for UK road freight

open access: yesTransportation Engineering, 2022
An Electric Road System (ERS)—comprising a network of overhead cables to charge Heavy Goods Vehicles (HGVs) via a pantograph pick-up—is a cost-competitive solution to rapidly decarbonise the UK road freight sector. A major benefit over conventional battery electric HGVs is the reduction in battery capacities needed to fulfil logistics needs.
Christopher de Saxe   +6 more
openaire   +2 more sources

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