Results 31 to 40 of about 3,700 (258)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Sensitivity analysis of impact model for road freight by the increase in the use of larger trucks in Spain

European Journal of Transport and Infrastructure Research, 2016
This study develops an impact model for road freight transport and aims to analyse the sensitivity of the results to the model parameters. Scenarios are simulated to study the effect of this model on road freight transport operations.
Pedro J. Pérez-Martínez, Regina M. Miranda   +1 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

RFID AS A TOOL OF COMPETITIVENESS INCREASE OF RAIL FREIGHT [PDF]

Acta Tecnología, 2016
Nowadays huge of goods is transported by road although there is requirement to greener logistic. Unfortunately if rail freight transport wants to be competitive to road transport, many changes must be done.
Romana Hricová
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Energy and emissions balance of modal shift in freight transport: A case study from the Central European region

Transportation Research Interdisciplinary Perspectives
Freight transport is a major contributor to energy consumption and greenhouse gas emissions in the European Union. Despite European Union strategies promoting a modal shift from road to rail, road freight still dominates in Central Europe.
Zdenka Bulková, Vladislav Zitrický, Vladimír Ľupták, Jan Brabec, Jan Pečman   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Implementation of the concept of green logistics reffering to it applications for road freight transport enterprises

Business: Theory and Practice, 2013
The article examines a scientific and practical problem concerning the ability to implement a concept of green logistics with reference to IT applications for Lithuanian road freight transport enterprises.
Aidas Vasilis Vasiliauskas, Virgilija Zinkevičiūtė, Eglė Šimonytė   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A Different Nested Logit Model Structure Consistent with Random Utility Theory for Various Freight Types – A Case Study for Istanbul

Promet (Zagreb), 2023
Freight transport significantly contributes to urban traffic but is often overlooked by decision-makers compared to passenger transport. Conventional transportation modelling studies often use aggregate approaches for freight transport, undoubtedly due ...
Berna Aksoy, Mustafa Gursoy
doaj   +1 more source