Results 151 to 160 of about 210,426 (263)

Pedestrian Crashes in the Northern Territory, Australia: A Detailed Epidemiological Analysis From 2013 to 2023. [PDF]

Health Promot J Austr
Clifford S, Lee KKS, Lamba G, Dadi A, Canty R, Wardle F, Ramsamy R, Wright CJC.   +7 more
europepmc   +1 more source

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

Advanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim, In Ah Kwon, Bo Seop Jeong, Hyo Seon Kim, Joo‐Hwan Park, Sung Jean Park, Sang‐Rae Lee, Youngki Lee, Dongwoo Khang   +8 more
wiley   +1 more source

Pelvis and lower extremity fractures related to 4-wheeled off-road vehicles: trends from the national electronic injury surveillance system database. [PDF]

OTA Int
Rivenbark E, Lenz C, Esparza A, Cummings GR, Johnson JE.   +4 more
europepmc   +1 more source

Friction Injuries Following Road Accidents [PDF]

BMJ, 1952
openaire   +2 more sources

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Epidemiology of Orthopaedic Trauma Admissions From the Emergency Department of a Major Trauma Centre in Rural North India. [PDF]

Cureus
Singh J, Kumar D, Mittal A, Singh SK, Yadav S, Rajput AK, Gupta PK, Saroj AK.   +7 more
europepmc   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

The rising burden of non-motor vehicle crashes: An emerging challenge for road traffic injury prevention in China, 1997-2023. [PDF]

Public Health Pract (Oxf)
Deng R, Yu S, Lin J, Yang Z, Ye W.
europepmc   +1 more source

Hemoglobin's α‐Helix‐to‐β‐Sheet Transition Enables Targeted mRNA Delivery to the Lung

Advanced Science, EarlyView.
Acidic heating converts hemoglobin into β‐sheet‐rich fibrils with positively charged surfaces. These hemoglobin fibrils electrostatically complex IL‐11 scFv mRNA, selectively bind circulating platelets, and hitchhike to the lung, where they are enriched in fibroblasts.
Xihua Liu, Saiya Li, Guodong Wu, Shuangjian Li, Long Shuang Huang, Xiaoyang Li, Yiguo Zhao, Wei Lu, Cuixia Sun, Qin Cao, Yapeng Fang, Yiping Cao   +11 more
wiley   +1 more source

Personality traits as behavioral determinants of road traffic injury risk: a mechanism-informed cross-sectional analysis. [PDF]

Front Public Health
Cheong A, Nik Ab Rahman NH, Wan Mohd Zuhdi WHI.   +2 more
europepmc   +1 more source