Results 221 to 230 of about 2,006,746 (285)

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

open access: yesAdvanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang   +12 more
wiley   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang   +22 more
wiley   +1 more source

Fatal traumatic injury patterns in free-roaming cats: an anatomopathological study of 40 cases. [PDF]

open access: yesBMC Vet Res
Sampaio RAG   +8 more
europepmc   +1 more source

Motorcycle-Related Fatalities: A Systematic Review and Structured Narrative Synthesis. [PDF]

open access: yesCureus
Tousia A   +4 more
europepmc   +1 more source

Crash causation, countermeasures, and strengthening of road safety policy in Nepal: a narrative review. [PDF]

open access: yesFront Public Health
Nepal S   +5 more
europepmc   +1 more source

Road traffic injury: prioritising interventions.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2008
Matzopoulos, R   +2 more
openaire   +2 more sources

Evaluation of trauma-related mortality in Peshawar, Pakistan: a study at Khyber Teaching Hospital. [PDF]

open access: yesTrauma Surg Acute Care Open
Ullah R   +11 more
europepmc   +1 more source

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