Results 61 to 70 of about 3,405,272 (348)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Water incident related hospital activity across England between 1997/8 and 2003/4: a retrospective descriptive study [PDF]

, 2006
Every year in the United Kingdom, 10,000 people will die from accidental injury and the treatment of these injuries will cost the NHS £2 billion and the consequences of injuries received at home cost society a further £25 billion [1].
British Medical Association, Department of Health, E Towner, Holly Henderson, I Mackie, J Steensberg, M Peden, N Saunders, RA Brenner, Richard C Wilson, SP Baker, UNICEF, World Health Organisation (WHO), World Health Organisation (WHO)   +13 more
core   +3 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Factors Associated with Road traffic Injuries in Tanzania. [PDF]

, 2016
Injuries represent a significant cause of morbidity and mortality worldwide and road traffic crashes accounts for a significant proportion of these injuries. Tanzania is among the countries with high rates of road traffic crashes.
Boniface, Respicious, Kiloloma, Othman, Munthali, Victoria, Museru, Lawrence   +3 more
core   +3 more sources

Overview of findings from a 2-year study of claimants who had sustained a mild or moderate injury in a road traffic crash: prospective study

BMC Research Notes, 2017
BackgroundStudies have shown that in people injured in a road traffic crash, persistent symptoms are common and can lead to significant ongoing personal impact.
B. Gopinath, J. Jagnoor, N. Elbers, I. Cameron   +3 more
semanticscholar   +1 more source

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao, Zhuoma Danzhen, Yao Li, Junyu Zhu, Lan Chu, Zhang Yang   +5 more
wiley   +1 more source

Comparative Study of Stewardship of Road Traffic Injuries Prevention with a Focus on the Role of Health System; Three Pioneer Countries and Three Similar to Iran [PDF]

Bulletin of Emergency and Trauma, 2019
Objective: To compare the stewardship of road traffic accidents (RTIs) prevention in three pioneer countries and three similar ones to Iran.Methods: In this descriptive comparative study, the United States of America, Sweden, and Brazil as the pioneer ...
Saber Azami-Aghdash, Homayoun Sadeghi-Bazarghani, Ramin Rezapour, Mahdiyeh Heydari, Naser Derakhshani   +4 more
doaj   +1 more source

Persistent vegetative state secondary to a motor vehicle accident [PDF]

, 2012
The case presents a young girl who was involved in a road traffic accident. Despite being alive at present, her body cannot perform any basic functions since she is in a persistent vegetative state.
Abela, Franklin, Dimech, Anthony
core  

Clinical Epidemiology of Head Injury from Road-Traffic Trauma in a Developing Country in the Current Era

Frontiers in Neurology, 2017
Objectives Africa and other Asian low middle-income countries account for the greatest burden of the global road-traffic injury (RTI)-related head injury (HI).
A. Adeleye, Millicent Ogun
semanticscholar   +1 more source

Physician Referral Patterns to Physical Therapists for Managing Knee Osteoarthritis: A Retrospective Analysis of Electronic Health Records from an Integrated Health System

Arthritis Care &Research, Accepted Article.
Objectives This study aims to describe the frequency and timing of physician referrals to physical therapists (PT) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja, Joel M. Stevans, Gustavo J. Almeida, Clair Smith, Janet K. Freburger   +4 more
wiley   +1 more source