Results 41 to 50 of about 350,029 (262)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Tools for road infrastructure safety management in poland

MATEC Web of Conferences, 2017
Road safety can be improved by implementing principles of road safety infrastructure management (RIS) on the network of European roads as adopted in the Directive.
Kustra Wojciech, Michalski Lech
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

IMPLEMENTATION OF ASSET MANAGEMENT IN ROAD ADMINISTRATION OF SLOVAK REPUBLIC [PDF]

Acta Logistica, 2014
The article presents basic principles and solutions for the application of Asset Management as part of road administration in Slovakia. It deals with application of Assets management methods and best practices of global trends in road maintenance ...
Ľubomír Pepucha, Ľuboš Remek, Juraj Šrámek, Peter Danišovič, Martin Slabej, Michal Grinč   +5 more
doaj  

Partitioning urban road network based on travel speed correlation

International Journal of Transportation Science and Technology, 2021
Urban traffic management is increasingly critical in the future to ensure the livability, efficiency, and sustainability of the city. Urban road network partition is a fundamental step in traffic management and it directly affects the effectiveness of ...
Qing Yu, Weifeng Li, Dongyuan Yang, Haoran Zhang   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Road safety management and interventions in Africa: Is there a correlation between management performance and traffic fatalities?

Transportation Research Interdisciplinary Perspectives
The primary aim of this article is to deepen understanding of road safety management in Africa and its relationship with traffic fatalities on the continent.
Robert Tama Lisinge, Davide Shingo Usami, Luca Persia   +2 more
doaj   +1 more source

Pemodelan Estimasi Kerusakan Jalan Metode Markov

Rekayasa Sipil, 2023
Roads with damaged conditions can cause traffic accidents and hinder society's economic and social progress. Roads that are left hurt and no repairs will further worsen the condition of these roads.
Rindah Intansari Mukti, Ludfi Djakfar, M. Zainul Arifin   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source