Results 81 to 90 of about 1,135,376 (250)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

The cluster analysis in the aluminium industry with K-means method: an application for Bahrain

open access: yesCogent Business & Management
This study examines the utilization of the K-means clustering method to analyze Bahrain’s aluminum industry. In addition, this study emphasizes the importance of clustering in understanding productivity, quality, and competitiveness within the sector ...
Haitham Al Qahtani, Jayendira P. Sankar
doaj   +1 more source

Stewardship Plan for the 5 Corners Reserve, Lee, NH [PDF]

open access: yes, 2010
The 20.7–acre Lee Five Corners Reserve (Reserve) is located north of Route 4 and west of Snell Road in the northern “Five Corners” region of Lee, New Hampshire. The property is accessed at the end of Old Concord Turnpike, which leads northwest from Snell
Snyder, Ellen
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Social capital: a road map of theoretical frameworks and empirical limitations [PDF]

open access: yes, 2013
The general idea of social capital is that relationships matter. In this sense, trust, cooperation and reciprocity involved in these relationships can have a positive impact on the wealth of the society by reducing transaction costs, facilitating ...
Andriani, Luca
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Ayer Hitam Forest (AHFR) from space using satellite remote sensing [PDF]

open access: yes, 1999
There is a high demand to map and monitor the land use and assess their condition for ecological and economic reasons. Information on existing land and cover and their spatial distribution is a pre-requisite for any planning, development and management ...
Ismail, Mohd Hasmadi   +1 more
core  

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

Identifying and Prioritizing Important necessities for formulation of Open Source Software Roadmap in Iran ررررررررر [PDF]

open access: yesمطالعات مدیریت کسب و کار هوشمند, 2012
According to extension of using open source software packages in recent years especially in developing countries, preparing a comprehensive roadmap for open source software development in Iran is essential.
Mohammad Reza Taghva   +2 more
doaj  

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