Results 71 to 80 of about 2,048,211 (327)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

The environmental impact evaluation on the application of permeable pavement based on life cycle analysis

International Journal of Transportation Science and Technology, 2019
Conventional pavement, namely concrete and asphalt pavements, usually necessitate considerable energy inputs during construction. Due to increasing road coverage in cities and the impervious feature of conventional pavements, the heat island effect is ...
Guoyang Lu, Yuhong Wang, Hui Li, Dawei Wang, Markus Oeser   +4 more
doaj   +1 more source

Evaluation of low-noise-drainage pavements with varied aggregate sizes: A case study in South Korea

Case Studies in Construction Materials, 2023
This research addresses the need for quieter and safer road environments by evaluating low-noise-drainage pavements with varying coarse aggregate sizes. Thorough physical property tests were conducted on pavements with aggregate sizes of 8 mm, 10 mm, 13 ...
Sang-Yum Lee, Yun Yung Man, Tri Ho Minh Le   +2 more
doaj   +1 more source

Self-healing Asphalt for Road Pavements

, 2020
This paper presents a unique self-healing system for asphalt pavement which employs compartmented calcium-alginate fibres encapsulating an asphalt binder healing agent (rejuvenator). This system presents a novel method of incorporating rejuvenators into asphalt pavement mixtures.
Tabakovic, A. (author), Schlangen, E. (author)   +1 more
openaire   +5 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Analysis of skid resistance of road pavements in the initial period of its life

Budownictwo i Architektura, 2014
Changes of microtexture and macrotexture significantly influence skid resistance of road pavements. It takes place especially during the initial period of pavement life.
Marta Wasilewska
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

Advanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal, Michael M. Becker, Sarah C. L. Fischer   +2 more
wiley   +1 more source

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

Advanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara, Vincent Rat, Quentin Dubreuil, Patrice Valorge, Simon Goutier, Alain Denoirjean, Olivier Messe, Céline Ruelle, Jean‐Philippe Poli   +8 more
wiley   +1 more source

Incorporating Increased Road User Costs into Pavement Management Modeling: A Case Study of Two-Lane Rural Highways

Infrastructures
The impact of increased road user costs on optimal pavement rehabilitation plans has been investigated using a simplified pavement management model.
Khaled A. Abaza, Mohamed S. Yamany
doaj   +1 more source