Results 211 to 220 of about 1,102,288 (301)

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

Dataset for surface and subsurface characterization of removable urban pavements with a functionalized surface (RUP-FS) using multi-technique measurements. [PDF]

Data Brief
Andreoli G, Skamantzari M, Schmidt F, Ihamouten A, Cothenet A, Gennesseaux E, Bakalos N, Sedran T.   +7 more
europepmc   +1 more source

Laser scanning on road pavements: a new approach for characterizing surface texture. [PDF]

Sensors (Basel), 2012
Bitelli G, Simone A, Girardi F, Lantieri C.   +3 more
europepmc   +1 more source

Patient‐Derived Glioblastoma Organoids for AI‐Guided Prediction of Therapeutic Response

Advanced Science, EarlyView.
Patient‐derived glioblastoma organoids provide clinically relevant models that preserve tumor heterogeneity and enable integrated AI‐driven analysis of imaging, molecular, and treatment‐response data. Their convergence with advanced analytics supports predictive, personalized therapeutic strategies and may accelerate translation from patient‐specific ...
Sandbhor Puja, Arun Bhavyadharshini, John Geofrey, Mudliyar Siddharth, Ghanekar Shubham, Moyiadi Aliasgar, Shetty Prakash, Singh Vikas, Sadwani Nidhisha, Garg Akshohini, Sahay Ayushi, Chatterjee Abhishek, Epari Sridhar, Gupta Tejpal, Dasgupta Archya, Goda Jayant   +15 more
wiley   +1 more source

A Comprehensive Review of Rollpave Pavement Technology: Current Research, Practices and Challenges. [PDF]

Materials (Basel)
Jia Y, Lan M, Wu Z, Lian H, Si C, Gao Y, Wang S, Gu L, Li Z.   +8 more
europepmc   +1 more source

COMPARISION OF ADVANCED (GEOSYNTHETIC) ROAD PAVEMENT AND CONVENTIONAL (ASPHALT/BITUMEN) ROAD PAVEMENT

International Journal of Advance Engineering and Research Development, 2017
openaire   +1 more source

A Compact and Fast Single‐Spike TTFS Encoder With Ultralow Operating Voltage for Efficient Neuromorphic Fourier Transform

Advanced Science, EarlyView.
A Pt/TaOx/V single‐spike TTFS encoder achieves ultralow‐voltage (∼0.35 V), high‐speed (∼100 ns) operation with simplified circuitry. Integrating bipolar nonuniform temporal encoding with a spiking‐DFT neuron model enables a neuromorphic FFT framework. Device‐calibrated simulations demonstrate high spectral fidelity across multitone, speech, and chirp ...
Yang Wu, Qi Wei, Junfeng Zhang, Lirou Su, Ning Mao, Beibei Huang, Jiaying Chen, Dian Huang, Shengzhong Feng, Yishu Zhang, Shuai Zhong   +10 more
wiley   +1 more source

Mechanochemical Engineered Sulfur Copolymers Onto Group 13 and Related Fillers Through Lewis Acid‐Base Pairing

Advanced Science, EarlyView.
Green mechanochemical copolymerization was developed for universal interfacial modification of Group 13 and related fillers. By leveraging Lewis acid–base coordination to anchor sulfur‐containing polymers—validated via multiscale characterization and DFT—this versatile method boosts performance across liquid fuels, thermal‐shielding materials, and ...
Chen Wang, Xiaoyang Shao, Zixuan Lei, Ruoqing Zhao, Xiaozhong Bao, Shuiping Zhou, Wen Ao, Zhenhua Wang   +7 more
wiley   +1 more source

Investigation on Mechanical and Fatigue Performance of Large-Thickness Flexible Base Layer Asphalt Pavement. [PDF]

Materials (Basel)
Nie Y, Wang S, Zhang R, He B, Yao G, Chen L.   +5 more
europepmc   +1 more source

Magnetic Thermal Ablation Combined with Temporally Coordinated CpG Immunotherapy Promotes cDC1‐Dependent Immune Priming in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Novel PLA@Fe3O4 magnetic microspheres were developed for transarterial magnetic hyperthermia ablation (MTA) of hepatocellular carcinoma. While destroying local tumors and inducing immunogenic cell death (ICD), MTA combined with early CpG adjuvant administration significantly promotes cDC1‐dependent immune priming. This synergistic mechanism effectively
Jiakun Yang, Nailin Yang, Shuangshuang Ji, Siping Meng, Di Wang, Wenjun Liang, Xuming Bai, Yong Jin, Xingwei Sun   +8 more
wiley   +1 more source