Results 91 to 100 of about 486,242 (343)
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
Activity-Based Computation of Marginal Noise Exposure Costs : Implications for Traffic Management [PDF]
, 2016 In this paper, an innovative simulation-based approach is presented to calculate optimal dynamic, road- and vehicle-specific tolls on the basis of marginal traffic noise exposures.
Kaddoura, Ihab, Nagel, Kai
core +1 more source
Advanced Science, EarlyView.This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin +12 more
wiley +1 more source
Environmental Health Perspectives, 2019 Background: Surrounding green, air pollution, and noise have been associated with cardiometabolic diseases, but most studies have assessed only one of these correlated exposures.
J. Klompmaker +8 more
semanticscholar +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Noise and Health, 2018 Aim: To examine the stroke risks associated with aircraft, road traffic, and railway noise exposure in a large case–control study. Materials and Methods: All people aged ≥40 years living around the Frankfurt airport that were insured by one of three ...
Anna Lene Seidler +8 more
doaj +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Residential road traffic noise exposure and colorectal cancer survival - A Danish cohort study.
PLoS ONE, 2017 BackgroundResidential traffic noise exposure may entail sleep disruption and compromised circadian functioning; two factors which have been associated with a poor colorectal cancer (CRC) prognosis.
Nina Roswall +6 more
doaj +1 more source
Road traffic noise and cardiovascular risk
Noise and Health, 2008 Studies on the association between community noise and cardiovascular risk were subjected to a meta-analysis for deriving a common dose-effect curve. Peer-reviewed articles, objective assessment of exposure and outcome as well as control for confounding and multiple exposure categories were all necessary inclusion criteria.
openaire +2 more sources
Recent Developments in Sonic Crystals as Barriers for Road Traffic Noise Mitigation
Environments, 2019 Noise barriers are the most widespread solution to mitigate noise produced by the continuous growth of vehicular traffic, thus reducing the large number of people exposed to it and avoiding unpleasant effects on health.
Luca Fredianelli +2 more
semanticscholar +1 more source