Results 21 to 30 of about 58,050 (219)

Extended Measurement Methods for Onboard Detection of Brake Disc Deformation

open access: yesEngineering Proceedings
Runout is a common failure of brake discs. The detection of this fault usually depends on the driver, as there is a vibration in the car and on the brake pedal.
Péter Őri, István Lakatos
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Research on the Dynamic and Energetic Performances of an Electric SUV in Real Driving Conditions

open access: yesDesigns
Electric vehicles have a limited driving range compared to conventional vehicles. This paper aims to present a particular study of the performances of electric vehicles based on real driving conditions on a cycle carried out using the general conditions ...
Alexandru-Adrian Ancuta   +2 more
doaj   +1 more source

The Effect of Road Hump in Reducing Speed of Motorcars in a Residential Area in Kuala Lumpur [PDF]

open access: yesJournal of Design and the Built Environment, 2013
In its most simple terms, traffic calming is about preserving the functions of local streets. As local streets are intended to provide primarily land-access services, hence, when traffic begins to use local streets for through movements, traffic volume ...
Noor Alyani Yaacob   +1 more
doaj  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Multi-Input CNN for Vision-Based In Situ Analysis of Extraterrestrial Surface Composition

open access: yesComputer Assisted Methods in Engineering and Science
Earth’s natural resources are finite, which is why engineers and scientists are increasingly directing their attention to the extraction of materials from celestial bodies.
Kacper MARCINIAK   +6 more
doaj   +1 more source

Vision-based investigation of road traffic and violations at urban roundabout in India using UAV video: A case study

open access: yesTransportation Engineering, 2023
In the past decade, the number of vehicles in India has increased exponentially; however, road infrastructure has not scaled proportionately. As a result, road traffic problems such as congestion on urban roads, dangerous traffic violations, and road ...
Yagnik M Bhavsar   +3 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

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