Results 121 to 130 of about 81,389 (268)
Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation
Advanced Science, EarlyView.Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan +11 more
wiley +1 more source
Roadmap for a European healthgrid.
Studies in health technology and informatics, 2007 This paper proposes a 10-year roadmap to achieve the goal to offer to healthcare professionals an environment created through the sharing of resources, in which heterogeneous and dispersed health data as well as applications can be accessed by all users as a tailored information providing system according to their authorisation and without loss of ...
Vincent Breton +6 more
openaire +3 more sources
Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction
Advanced Science, EarlyView.Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen +5 more
wiley +1 more source
Advanced Science, EarlyView.HfO2‐based ferroelectrics exhibit wake‐up and fatigue behaviors during electrical cycling, significantly affecting device endurance and reliability. These phenomena are governed by defect dynamics, including oxygen vacancy redistribution and charge trapping.
Hongseok Kim +6 more
wiley +1 more source
Advanced Science, EarlyView.A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi +12 more
wiley +1 more source
Using large language models to enhance clinically-driven missing data recovery algorithms in electronic health records. [PDF]
JAMIA OpenLotspeich SC +5 more
europepmc +1 more source
Maximizing the Energy Output of Soft Electrohydraulic Generators
Advanced Science, EarlyView.Many energy resources cannot be viably harvested with electromagnetic generators. This article evaluates the potential of soft electrohydraulic generators as an alternative approach for energy capture. An analytical model charts their operational limits and a rigorous experimental study results in new performance benchmarks with maximum specific energy
Sophie Kirkman +7 more
wiley +1 more source
Porous Ultralow‐κ sp2‐Bonded Boron Nitride Thin Films as Copper Diffusion Barriers
Advanced Science, EarlyView.Porous sp2‐bonded boron nitride (p‐BN) thin films with an ultralow dielectric constant (κ = 1.77) are directly grown on Si substrates via RF magnetron sputtering. The films feature uniform nanopores (1.85 nm), high mechanical stability, hydrophobicity, and excellent Cu diffusion barrier performance even at 3 nm thickness, offering a promising solution ...
Caiyun Liu +11 more
wiley +1 more source
Pedal access for genicular artery embolization: technique description and procedural workflow. [PDF]
J Surg Case RepMargni M +3 more
europepmc +1 more source