Results 51 to 60 of about 476,676 (296)

Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients The ROADMAP Study 2-Year Results [PDF]

, 2017
OBJECTIVES The authors sought to provide the pre-specified primary endpoint of the ROADMAP (Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients) trial at 2 years ...
Boyle, Andrew J., Bruckner, Brian A., Chuang, Joyce, Estep, Jerry D., Farrar, David J., Haas, Donald C., Horstmanshof, Douglas A., Kasirajan, Vigneshwar, Lee, Sangjin, Long, James W., Milano, Carmelo A., Rogers, Joseph G., Selzman, Craig H., Shah, Keyur B., Starling, Randall C., Stehlik, Josef   +15 more
core   +2 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Decadal changes in meteorological extremes and environmental consequences in the Caspian Sea Region

Discover Atmosphere
Using data from the MERRA-2 database, the study identifies a clear warming trend in August, with significant peaks in the annual average air temperature in 2010 (28.3 °C) and 2021 (27.9 °C) in the Caspian Sea. Concurrently, the Caspian Sea’s water levels
Farahnaz Fazel-Rastgar, Venkataraman Sivakumar, Masoud Rostami, Bijan Fallah   +3 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A Safe and rapid technique for pacemaker İmplantation: Roadmap-guided subclavian vein puncture

International Journal of the Cardiovascular Academy, 2019
Objective: Widely used method is blinded puncture of subclavian vein, but the complication rate is high in this method. In this study, we aimed to demonstrate the effect of roadmap use during implantation of permanent pacemaker on the success rate, speed
Hakan Gunes, Mahmut Tuna Katırcıbası, Akif Serhat Balcıoğlu, Ekrem Aksu, Abdullah Sokmen, Gulizar Sokmen, Murat Kerkutluoglu, Ahmet Çağrı Aykan, Sami Ozgul   +8 more
doaj   +1 more source

A Roadmap for Systematically Identifying Opportunities in Ecosystems Using Scientific Publications Data

Technology Innovation Management Review, 2021
Opportunity identification is a continuous process in ecosystems. However, ambiguities and challenges associated with knowledge exploration and exploitation can retard opportunity recognition processes. This in turn may culminate in excessive expenditure
Behrooz Khademi, Hannele Lampela, Kosmas X. Smyrnios   +2 more
doaj   +1 more source

U.S. SDG Data Revolution Roadmap [PDF]

, 2017
One year after adopting the SDGs, in an addendum to its Open Government National Action Plan, the U.S. Government committed to develop an SDG Data Revolution Roadmap that "charts the future course of efforts to fill data gaps and build capacity to use ...
Aditya Agrawal, Audrey Ariss, Joel Gurin, Katherine Garcia, Laura Manley   +4 more
core  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Roadmap to Majorana surface codes

, 2016
Surface codes offer a very promising avenue towards fault-tolerant quantum computation. We argue that two-dimensional interacting networks of Majorana bound states in topological superconductor/semiconductor heterostructures hold several distinct ...
Altland, A., Egger, R., Flensberg, K., Landau, L. A., Plugge, S., Sela, E.   +5 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source