Results 101 to 110 of about 21,431 (278)

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum   +5 more
wiley   +1 more source

The great training robbery [PDF]

open access: yesBritish Journal of General Practice, 2019
I chose to train in general practice for a multitude of powerful and positive reasons but increasingly feel the victim of a great training robbery. Many problems have beset the programme, with the recent House of Lords report calling it unfit for purpose.1 There is however nothing more illustrative of the depth of despair than the lived experiences of ...
openaire   +3 more sources

Infusion rate adjustment in enzyme replacement therapy with pabinafusp alfa for mucopolysaccharidosis II

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Enzyme replacement therapy (ERT) for mucopolysaccharidosis II (MPS II) requires long‐term, weekly intravenous infusions often lasting over 3 h each time, which can burden paediatric patients and caregivers and negatively affect their quality of life and treatment compliance.
Kimitoshi Nakamura   +6 more
wiley   +1 more source

[News Clip: Worth robbery] [PDF]

open access: yes, 1958
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about a Fort Worth grocery store ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

[News Clip: Robbery] [PDF]

open access: yes, 1956
Video footage from the WBAP-TV station in Fort Worth, Texas, covering a news story about a robbery at a liquor store in Dallas. An African American man robbed sixty-six-year-old P. M.
WBAP-TV (Television station : Fort Worth, Tex.)
core   +2 more sources

Exploring individualized crovalimab dosing in PNH through in silico modelling: Potential for improved convenience and cost efficiency

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, acquired haematopoietic stem cell disorder. Crovalimab, a complement C5‐inhibitor, is approved for PNH and can be self‐administered subcutaneously every 4 weeks, offering a more convenient route than intravenous C5‐inhibitors.
Mendy ter Avest   +4 more
wiley   +1 more source

[News Clip: Bank robbery] [PDF]

open access: yes, 1959
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about Melvin Raymond Paige being caught by Dallas police after a bank ...
WBAP-TV (Television station : Fort Worth, Tex.)
core   +2 more sources

Dva značajna izvora o zbivanjima u Rogatici i njenoj okolini 1941. godine [PDF]

open access: yesHistorijska Misao, 2017
This paper presents the reconstruction of circumstances and events in Rogatica and its surroundings in 1941 on the basis of two sources that have not been used in historical literature devoted to developments in Bosnia and Herzegovina from 1941 to 1945 ...
Adnan Jahić
doaj  

N‐acetylcysteine for non‐paracetamol‐induced acute liver failure in children: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot   +7 more
wiley   +1 more source

Reception Baseline Assessment and ‘small acts’ of micro‐resistance

open access: yesBritish Educational Research Journal, EarlyView.
Abstract In September 2021, following the global COVID‐19 pandemic, the Department for Education introduced a national standardised digital Reception Baseline Assessment (RBA) for all English 4‐year‐old children. We analyse RBA and its associated Quality Monitoring Visits, as a further intensification of the new public management of early years ...
Guy Roberts‐Holmes   +2 more
wiley   +1 more source

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