Results 51 to 60 of about 4,724,591 (255)
Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang +18 more
wiley +1 more source
La investigación ecológica de las comunidades locales
Los trabajos científicos e institucionales de Robert Park marcan uno de los períodos más sugerentes de la investigación sociológica. Park completa el giro empírico iniciado por la primera generación del departamento de sociología de la Universidad de ...
Emilio Martínez Gutiérrez
doaj
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Photo‐Degradable Polyester Networks and Multi‐Photon Printed Objects Based on Cyclic Ketene Acetals
The current work introduces a photoreversible polyester network derived from radical ring‐opening polymerization of cyclic ketene acetals. It combines photoreversible cross‐linking with initiator‐free multi‐photon printing. Reversible network formation, tunable mechanical properties, and selective degradation highlight its potential as a versatile ...
Till Meissner +5 more
wiley +1 more source
Este trabalho apresenta um estudo do Welcome Park, uma espécie de memorial projetado pelo escritório norte-americano de Robert Venturi, Denise Scott-Brown e John Rauch.
Fernando Atique
doaj
Protein‐Nanoarchitectures for Low‐Field Intracellular Electro‐Immunomodulation
DHQ‐SDH‐mediated binding of AuNPs drives the formation of interconnected, chain‐like nanoarchitectures with enhanced electrical conductivity. These conductive assemblies undergo macrophage uptake and enable low‐field electrical stimulation, promoting M1‐to‐M2 phenotypic switching with decreased iNOS and increased CD206 expression. Such protein‐mediated
Viktoriya Pakharenko +7 more
wiley +1 more source
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman +9 more
wiley +1 more source
Lightweight Solution to Generate Accurate Lanelet Maps
As automated driving technologies become more mature, there is an increasing reliance on digital maps to support safe and efficient driving. Sensors like cameras and radars can be limited by occlusions, lighting conditions, or weather, and often fall ...
Gergő Ignéczi +2 more
doaj +1 more source
Robert geranium flower, probably in Olympic National Park, date unknown
Herb Robert; Geranium robertianum.
Unknown
core
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
wiley +1 more source

