Results 111 to 120 of about 109,310 (329)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

open access: yesAdvanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance   +17 more
wiley   +1 more source

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

open access: yesAdvanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger   +17 more
wiley   +1 more source

Absolutely stable difference scheme for the delay partial differential equation with involution and Robin boundary condition

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
This paper examines the initial value problem for a third-order delay partial differential equation with involution and Robin boundary condition. We construct a first-order accurate difference scheme to obtain the numerical solution for this equation ...
A. Ashyralyev, S. Ibrahim, E. Hincal
doaj   +1 more source

Nitsche's method for a Robin boundary value problem in a smooth domain

open access: yes, 2019
We prove several optimal-order error estimates for the finite element method applied to an inhomogeneous Robin boundary value problem for the Poisson equation defined in a smooth bounded domain in $\mathbb{R}^n$, $n=2,3$.
Chiba, Yuki, Saito, Norikazu
core  

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

open access: yesAdvanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo   +14 more
wiley   +1 more source

Multivalued problem with Robin boundary condition involving diffuse measure data and variable exponent

open access: yesAdvances in Nonlinear Analysis, 2014
We study a nonlinear elliptic problem with Robin type boundary condition, governed by a general Leray–Lions operator with variable exponents and diffuse Radon measure data which does not charge the sets of zero p(·)-capacity.
Ouaro Stanislas   +2 more
doaj   +1 more source

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