Recombinant Human Neuregulin1‐β1 Significantly Reduces Schwannoma Growth in Mice
Annals of Neurology, EarlyView.rhNRGβ1‐Replacement‐Therapy: Under physiological conditions, NRGβ1 is expressed on axons (in orange), where it activates ERBB2 receptors, facilitating successful nerve regeneration following injury. However, loss of NF2 leads to a reduction in NRGβ1‐expression and increased ErbB2 levels on Schwann cells (in green), which contributes to schwannoma ...
Julia P. Bischoff +7 more
wiley +1 more source
Comparison principles for the time-fractional diffusion equations with the Robin boundary conditions. Part II: Semilinear equations [PDF]
Yuri Luchko, Masahiro Yamamoto
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Annals of Neurology, EarlyView.Objective Age of symptom onset is highly variable in familial frontotemporal lobar degeneration (f‐FTLD). Accurate prediction of onset would inform clinical management and trial enrollment. Prior studies indicate that individualized maps of brain atrophy can predict conversion to dementia in f‐FTLD.
Shubir Dutt +82 more
wiley +1 more source
Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort
Annals of Neurology, EarlyView.Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov +42 more
wiley +1 more source
Growing sandpile problem with Dirichlet and Fourier boundary conditions
Electronic Journal of Differential Equations, 2017 In this work, we study the Prigozhin model for growing sandpile with mixed boundary conditions and an arbitrary time dependent angle of repose. On one part of the boundary the homogeneous Dirichlet boundary condition is provided, on the other one the ...
Estelle Nassouri +2 more
doaj
Homogeneous Robin Boundary Conditions and Discrete Spectrum of Fractional Eigenvalue Problem
, 2018 Małgorzata Klimek
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ON CORRECTORS FOR SPECTRAL PROBLEMS IN THE HOMOGENIZATION OF ROBIN BOUNDARY CONDITIONS WITH VERY LARGE PARAMETERS [PDF]
, 2013 Delfina Gómez +3 more
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Robin boundary conditions in shape optimization
, 2015 The present thesis is concerned with the problem of proving the existence of optimal domains for functionals subjected to Robin Boundary conditions. We treat both cases of positive and negative Robin parameters. In the case of positive Robin parameters we prove the existence of a minimizing domain in a class of Lipschitz domains of given measure, that ...
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Asymptotic behavior of null controllability cost for parabolic equations with vanishing diffusivity under Robin and Neumann boundary conditions [PDF]
Fouad Et-tahri +3 more
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Homogenization of a linear elastic body with rigid inclusions and a Robin type boundary conditions [PDF]
Lazarus Signing
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