Results 51 to 60 of about 6,950 (285)

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Quantum field theory on global anti-de Sitter space-time with Robin boundary conditions [PDF]

open access: yes, 2020
We compute the vacuum polarization for a massless, conformally coupled scalar field on the covering space of global, four-dimensional, anti-de Sitter space-time.
Morley, Thomas   +5 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Analysis of complex nonlinear reaction-diffusion equations [PDF]

open access: yes, 2008
A mathematical analysis has been carried out for some nonlinear reaction- diffusion equations on open bounded convex domains Ω C R(^d)(d < 3) with Robin boundary conditions- Existence, uniqueness and continuous dependence on initial data of weak and ...
Al-Ofl, Abdalaziz Saleem
core  

Dynamical large deviations for the boundary driven symmetric exclusion process with Robin boundary conditions [PDF]

open access: yes, 2022
International audienceIn this article, we consider a one-dimensional symmetric exclusion process in weak contact with reservoirs at the boundary. In the diffusive time-scaling the empirical measure evolves according to the heat equation with Robin ...
Gonçalves, Patrícia   +5 more
core   +1 more source

Impact of space-time curvature coupling on the vacuum energy induced by a magnetic topological defect in flat space-time of arbitrary dimension

open access: yesNuclear Physics B
We have investigated vacuum polarization of a quantized charged massive scalar field in the presence of a magnetic topological defect, modeled as an impenetrable tube of finite thickness carrying magnetic flux. At the tube’s surface, we imposed a general
V.M. Gorkavenko   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A Numerical Study of Burgers' Equation With Robin Boundary Conditions [PDF]

open access: yes, 2001
This thesis examines the numerical solution to Burgers' equation on a finite spatial domain with various boundary conditions. We first conduct experiments to confirm the numerical solutions observed by other researchers for Neumann boundary conditions.
Nguyen, Vinh Q.
core  

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Convergence of a Robin boundary approximation for a Cahn–Hilliard system with dynamic boundary conditions [PDF]

open access: yesNonlinearity, 2020
Abstract We prove the existence of unique weak solutions to an extension of a Cahn–Hilliard model proposed recently by C Liu and H Wu (2019 Arch. Ration. Mech. Anal. 233 167–247), in which the new dynamic boundary condition is further generalised with an ...
Patrik Knopf, Kei Fong Lam
openaire   +2 more sources

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