Abstract Global institutions are increasingly calling for an agroecological transition of our food systems to promote sustainable farmer livelihoods, safeguard agrobiodiversity and foster socio‐ecological resilience to a changing climate. Yet adoption remains limited, and there is a paucity of research examining how local conditions enable and ...
Gabriela Marie Garcia +5 more
wiley +1 more source
Inter-Rater Reliability Of Assigning A Pediatric Appendicitis Grade: An International Multicenter Study By The Canadian Consortium For Research In Pediatric Surgery (CanCORPS). [PDF]
St-Louis E +35 more
europepmc +1 more source
Tree-ring structure determines the temporal coordination between xylem growth and the gain in hydraulic conductivity in the outermost ring. [PDF]
Summary The study of seasonal xylem hydraulics has predominantly focused on embolism‐induced losses, whereas growth‐driven increases in hydraulic capacity have received little attention. We assessed the intra‐annual dynamics of xylem formation and gain of conductivity in the current‐year ring of three species with contrasting tree‐ring structure ...
Fernández-de-Uña L +4 more
europepmc +2 more sources
Stability and cooperativity in chimeric de novo TIM barrels via quarter swapping
Abstract The use of repetitive units as building blocks in protein design, mimicking evolutionary duplication events, is a valuable strategy that reduces structural complexity. Such modular designs offer an opportunity to dissect how local contributions are integrated in a context‐dependent manner.
Oscar Rodríguez‐Meza +5 more
wiley +1 more source
Food Handling Practices Among Food Businesses in Jigjiga, Eastern Ethiopia, During the COVID-19 Pandemic: Cross-Sectional Study. [PDF]
Farah AM +6 more
europepmc +1 more source
Functional thermodynamics govern the ligand binding to human cytosolic transport proteins
Abstract Traditional binding studies on cellular, molecular transporters often simplify the thermodynamics of binding processes. We present a method that combines spin probing, electron paramagnetic resonance (EPR) spectroscopy and spectral simulations with binding studies and thermodynamics for an in‐depth molecular view into ligand binding and ...
Sebastian Michler +3 more
wiley +1 more source
Coagulation Profiles Among Combined Oral Contraceptive User and Non-User Women Attending at Family Guidance Association of Ethiopia, Jigjiga Medium Clinic: A Comparative Cross-Sectional Study. [PDF]
Getu F +7 more
europepmc +1 more source
Mermaid syndrome: A case report in Somalia. [PDF]
Zeki Yaşar M +4 more
europepmc +1 more source
ERK autoinhibition mechanism informs a drug combination strategy
Abstract ERK is a key regulator in the MAPK pathway, controlling essential cell processes through dual‐phosphorylation‐based activation. We investigate the conformational equilibrium between inactive and active ERK states, which is controlled allosterically by its structurally unique C‐terminal L16 segment.
Clil Regev, Hyunbum Jang, Ruth Nussinov
wiley +1 more source

