Results 281 to 290 of about 3,396,076 (388)

Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition

open access: yesAdvanced Science, EarlyView.
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu   +12 more
wiley   +1 more source

Proteomics‐Empowered Microfluidic‐SERS Immunoassay for Identifying and Detecting Biomarkers of Micropapillary Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
The presence of a micropapillary (MPP) component is critical for lung adenocarcinoma (LUAD) surgery, yet reliable blood biomarkers remain lacking. This study integrates proteomics for biomarker identification, a nanomixing‐enhanced surface‐enhanced Raman spectroscopy (SERS) platform for sensitive detection, and machine learning for accurate ...
Dechun Zhang   +4 more
wiley   +1 more source

Efficacy of Vascular Ligation for the Prevention of Intra- and Postoperative Bleeding in Transoral Robotic Surgery for Oropharyngeal Cancer. [PDF]

open access: yesCancers (Basel)
Ueda T   +8 more
europepmc   +1 more source

Elastic Fiber Programming for Simplified Pneumatic Control in Soft Robots

open access: yesAdvanced Science, EarlyView.
This study introduces a novel approach to designing pneumatic soft actuators by leveraging elastic fiber programming to achieve tailored constitutive equations. Using pre‐stretched elastic fibers with varying properties and modurization, the soft robots can demonstrate diverse motions from a single pressure source. This simplifies control systems while
Xiaoli Yang   +7 more
wiley   +1 more source

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

open access: yesAdvanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu   +18 more
wiley   +1 more source

Voluminous hiatal hernias - the role of robotic surgery. [PDF]

open access: yesInnov Surg Sci
Dosch M, Chevallay M, Jung MK, Mönig S.
europepmc   +1 more source

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu   +10 more
wiley   +1 more source

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