Results 71 to 80 of about 3,429,179 (405)

Robotic large‐area optical biopsy imaging for automated detection of gastrointestinal cancers tested in tissue phantoms and ex vivo porcine bowel

Translational Biophotonics, 2023
Gastrointestinal endoscopy is a subjective procedure that frequently requires tissue samples for diagnosis. Contact optical biopsy (OB) techniques have the aim of providing direct diagnosis of endoscopic areas without excising tissue samples but lack the
Fernando B. Avila‐Rencoret, George P. Mylonas, Daniel S. Elson   +2 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

A core outcome set for localised prostate cancer effectiveness trials [PDF]

, 2017
Objective: To develop a core outcome set (COS) applicable for effectiveness trials of all interventions for localised prostate cancer. Background: Many treatments exist for localised prostate cancer, although it is unclear which offers the ...
Abel, Paul, Ahmed, Hashim U., Akehurst, Gary, Almquist, Robert, Beck, Karl, Bekema, Hanneke, Budd, David, Campbell, Marion, Canfield, Steven, Catto, James, Cornford, Philip, Cross, William, Dahm, Philipp, Ewen, Alexander, Grant, Judith, Heer, Rakesh, Hurst, David, Jones, Rob, Kockelbergh, Roger, Lam, Thomas, MacDonald, Graham, Mackie, Andrew, MacLennan, Sara, MacLennan, Steven, Mason, Malcolm, McClinton, Sam, McLaren, Duncan, McNeill, Alan, Mostafid, Hugh, Mottet, Nicolas, N'Dow, James, Pearce, Ian, Pennet, Linda, Ramsay, Craig, Royle, Justine, Schreuder, Hans, Stewart, Grant D., Vale, Luke, van der Poel, Henk, Wardlaw, Kevin, Wiegel, Thomas, Williamson, Paula R.   +41 more
core   +1 more source

Robot-Assisted Excision of a Pararectal Gastrointestinal Stromal Tumor in a Patient with Previous Ileal Neobladder

Case Reports in Urology, 2014
Gastrointestinal stromal tumors (GISTs) are the most frequent mesenchymal tumors of the gastrointestinal tract with surgical resection remaining the cornerstone of therapy.
A. Ploumidis, A. Mottrie, A. F. Spinoit, M. Gan, V. Ficarra, R. Andrianne   +5 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Impact of the Treatment of Serenoa repens, Solanum lycopersicum, Lycopene and Bromelain in Combination with Alfuzosin for Benign Prostatic Hyperplasia. Results from a Match-Paired Comparison Analysis

Uro, 2021
Background: Phytotherapeutic agents aroused an increasing interest either as alternative or in addition to conventional therapy in the management of BPH.
Luca Lambertini, Fabrizio Di Maida, Riccardo Tellini, Claudio Bisegna, Francesca Valastro, Antonio Andrea Grosso, Sabino Scelzi, Francesco Del Giudice, Matteo Ferro, Giacomo Maria Pirola, Marilena Gubbiotti, Lorenzo Masieri, Gian Maria Busetto, Ottavio de Cobelli, Andrea Minervini, Andrea Mari   +15 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Reducing Cost of Surgery by Avoiding Complications: the Model of Robotic Roux-en-Y Gastric Bypass [PDF]

, 2018
Background: Robotic surgery is a complex technology offering technical advantages over conventional methods. Still, clinical outcomes and financial issues have been subjects of debate.
Buchs, Nicolas, Chassot, Gilles, Hagen, Monika, Huber, Olivier, Iranmanesh, Pouya, Morel, Philippe, Pugin, Francois   +6 more
core  

ToolNet: Holistically-Nested Real-Time Segmentation of Robotic Surgical Tools [PDF]

, 2017
Real-time tool segmentation from endoscopic videos is an essential part of many computer-assisted robotic surgical systems and of critical importance in robotic surgical data science.
Attilakos, George, Deprest, Jan, Devreker, Alain, Fidon, Lucas, Garcia-Peraza-Herrera, Luis C., Gruijthuijsen, Caspar, Li, Wenqi, Ourselin, Sebastien, Poorten, Emmanuel Vander, Stoyanov, Danail, Vercauteren, Tom   +10 more
core   +3 more sources