Results 121 to 130 of about 683,774 (325)

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Reference intervals for serum immunoglobulins G, M and E levels in Brazilian children aged 1 to 10 years: a population-based study

Jornal de Pediatria
Objective: To determine the reference intervals (RI) for serum levels of IgG, IgM, and IgE in healthy children aged 1–10 years living in central Brazil. Method: A sample of 1743 healthy children was randomly selected from kindergartens and public schools.
Sandra Breder Assis, Natasha Slhessarenko, Cor Jesus Fernandes Fontes   +2 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

A New Robust Estimation Approach to Dual Response Surface Models

Düzce Üniversitesi Bilim ve Teknoloji Dergisi
Robust parameter design is one of the methods used to determine the optimum operating conditions of systems. In robust parameter design, dual response surface methodology plays a crucial role in identifying optimal settings that minimize variability ...
Elif Kozan
doaj   +1 more source

Condition monitoring for the quadruple water tank system using H-infinity Kalman Filtering

MATEC Web of Conferences, 2018
The problem of statistical fault diagnosis for the quadruple watertanks system is examined. The solution of the fault diagnosis problem for the dynamic model of the four-water tanks system is a non-trivial case, due to nonlinearities and the system’s ...
Rigatos Gerasimos, Serpanos Dimitrios, Siadimas Vasilios, Busawon Krishna, Gao Zhiwei, Siano Pierluigi, Abbaszadeh Masoud   +6 more
doaj   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Using Bootstrapping to Determine Artificial Neural Network Confidence Intervals—Case Study of Particleboard Internal Bond Determined from Production Data

Applied Sciences
Tensile strength perpendicular to the plane of the board (also known as the Internal Bond—IB), determined in accordance with standard EN 319, is one of the most critical properties in particleboard quality control.
Francisco García Fernández, Paloma de Palacios, Alberto García-Iruela, Luis García Esteban   +3 more
doaj   +1 more source

Incentives to learn calibration: a gender-dependent impact [PDF]

Miscalibration can be defined as the fact that people think that their knowledge is more precise than it actually is. In a typical miscalibration experiment, subjects are asked to provide subjective confidence intervals.
Guillaume Hollard, Marie-pierre Dargnies
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