Results 41 to 50 of about 1,356,793 (315)

Spatial Quantile Regression In Analysis Of Healthy Life Years In The European Union Countries [PDF]

open access: yes, 2016
The paper investigates the impact of the selected factors on the healthy life years of men and women in the EU countries. The multiple quantile spatial autoregression models are used in order to account for substantial differences in the healthy life ...
Orwat-Acedańska, Agnieszka   +1 more
core   +2 more sources

Can the buck always be passed to the highest level of clustering?

open access: yesBMC Medical Research Methodology, 2016
Background Clustering commonly affects the uncertainty of parameter estimates in epidemiological studies. Cluster-robust variance estimates (CRVE) are used to construct confidence intervals that account for single-level clustering, and are easily ...
Christian Bottomley   +3 more
doaj   +1 more source

One-Stage Multiple Comparisons with the Control for Exponential Median Lifetimes under Heteroscedasticity

open access: yesMathematics, 2020
When the additional sample for the second stage may not be available, one-stage multiple comparisons for exponential median lifetimes with the control under heteroscedasticity including one-sided and two-sided confidence intervals are proposed in this ...
Shu-Fei Wu
doaj   +1 more source

Robust nonparametric inference for the median

open access: yes, 2005
We consider the problem of constructing robust nonparametric confidence intervals and tests of hypothesis for the median when the data distribution is unknown and the data may contain a small fraction of contamination.
Yohai, Victor J., Zamar, Ruben H.
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Same or Different? Comparing the Coverage Rate of Five Different Approaches for Testing the Difference of Two Groups Means [PDF]

open access: yesTutorials in Quantitative Methods for Psychology
testing for statistically significant differences between two group means is one of the most common requirements in psychological research, for example, after an experiment has been conducted.
Bittmann, Felix
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Stacked survival models for residual lifetime data

open access: yesBMC Medical Research Methodology, 2022
When modelling the survival distribution of a disease for which the symptomatic progression of the associated condition is insidious, it is not always clear how to measure the failure/censoring times from some true date of disease onset.
James H. McVittie   +3 more
doaj   +1 more source

Robust Empirical Bayes Confidence Intervals [PDF]

open access: yes, 2021
We construct robust empirical Bayes confidence intervals (EBCIs) in a normal means problem. The intervals are centered at the usual linear empirical Bayes estimator, but use a critical value accounting for shrinkage. Parametric EBCIs that assume a normal
Armstrong, Timothy B.   +2 more
core  

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