Results 61 to 70 of about 1,356,793 (315)
FEBS Open Bio, EarlyView.Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash +6 more
wiley +1 more source
Variance Estimation for Logistic Regression in Case-cohort Studies
Journal of EpidemiologyBackground: The logistic regression analysis proposed by Schouten et al (Stat Med. 1993;12:1733–1745) has been a standard method in current statistical analysis of case-cohort studies, and it enables effective estimation of risk ratios from selected ...
Hisashi Noma
doaj +1 more source
BMC Medical Research Methodology, 2023 Background The effectiveness of malaria vector control interventions is often evaluated using cluster randomized trials (CRT) with outcomes assessed using repeated cross-sectional surveys.
Yongdong Ouyang +4 more
doaj +1 more source
A Robust Root Mean Square Standardized Effect Size in One-Way Fixed-Effects ANOVA [PDF]
, 2011 A robust Root Mean Square Standardized Effect Size (RMSSER) was developed to address the unsatisfactory performance of the Root Mean Square Standardized Effect Size. The coverage performances of the confidence intervals (CI) for RMSSER were investigated.
Algina, James, Zhang, Guili
core +2 more sources
FEBS Open Bio, EarlyView.This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Journal of Modern Power Systems and Clean EnergyInterval state estimation (ISE) can estimate state intervals of power systems according to confidence intervals of predicted pseudo-measurements, thereby analyzing the impact of uncertain pseudo-measurements on states.
Xu Zhang, Wei Yan, Meiqing Huo, Hui Li
doaj +1 more source
Robust Learning from Bites [PDF]
, 2005 Many robust statistical procedures have two drawbacks. Firstly, they are computer-intensive such that they can hardly be used for massive data sets. Secondly, robust confidence intervals for the estimated parameters or robust predictions according to the
Christmann, Andreas
core +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Nonparametric evaluation of quantitative traits in population-based association studies when the genetic model is unknown. [PDF]
PLoS ONE, 2012 Statistical association between a single nucleotide polymorphism (SNP) genotype and a quantitative trait in genome-wide association studies is usually assessed using a linear regression model, or, in the case of non-normally distributed trait values ...
Frank Konietschke +2 more
doaj +1 more source