Results 61 to 70 of about 666,183 (322)

Nonparametric Regression via StatLSSVM

Journal of Statistical Software, 2013
We present a new MATLAB toolbox under Windows and Linux for nonparametric regression estimation based on the statistical library for least squares support vector machines (StatLSSVM).
Kris De Brabanter, Johan Suykens, Bart De Moor   +2 more
doaj   +1 more source

RadVel: The Radial Velocity Modeling Toolkit [PDF]

, 2018
RadVel is an open source Python package for modeling Keplerian orbits in radial velocity (RV) time series. RadVel provides a convenient framework to fit RVs using maximum a posteriori optimization and to compute robust confidence intervals by sampling ...
Blunt, Sarah, Fulton, Benjamin J., Petigura, Erik A., Sinukoff, Evan   +3 more
core   +2 more sources

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Using Quantile Regression Approach to Analyze Price Movements of Agricultural Products in China

Journal of Integrative Agriculture, 2012
This paper studies how the price movements of pork, chicken and egg respond to those of related cost factors in short terms in Chinese market. We employ a linear quantile approach not only to explore potential data heteroscedasticity but also to generate
Gan-qiong LI, Shi-wei XU, Zhe-min LI, Yi-guo SUN, Xiao-xia DONG   +4 more
doaj   +1 more source

Stacked survival models for residual lifetime data

BMC Medical Research Methodology, 2022
When modelling the survival distribution of a disease for which the symptomatic progression of the associated condition is insidious, it is not always clear how to measure the failure/censoring times from some true date of disease onset.
James H. McVittie, David B. Wolfson, Vittorio Addona, Zhaoheng Li   +3 more
doaj   +1 more source

A Robust Root Mean Square Standardized Effect Size in One-Way Fixed-Effects ANOVA [PDF]

, 2011
A robust Root Mean Square Standardized Effect Size (RMSSER) was developed to address the unsatisfactory performance of the Root Mean Square Standardized Effect Size. The coverage performances of the confidence intervals (CI) for RMSSER were investigated.
Algina, James, Zhang, Guili
core   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

A robust and efficient algorithm to find profile likelihood confidence intervals [PDF]

, 2021
Samuel M. Fischer, Mark A. Lewis, Samuel M. Fischer, Mark A. Lewis   +3 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Variance Estimation for Logistic Regression in Case-cohort Studies

Journal of Epidemiology
Background: The logistic regression analysis proposed by Schouten et al (Stat Med. 1993;12:1733–1745) has been a standard method in current statistical analysis of case-cohort studies, and it enables effective estimation of risk ratios from selected ...
Hisashi Noma
doaj   +1 more source