Results 141 to 150 of about 368,778 (261)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Robust estimation of rice flag leaf inclination angle from SfM-MVS point clouds via ensemble skeleton extraction: validation in field and pot experiments. [PDF]

Plant Methods
Sun T, Zhou H, Lu Z, Li M, Cao J, Hu J, Zhang J, Pan Y, Bi R, Ye S, Wei M, Fang P, Yang Y, Jiang M, Zhang W.   +14 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Doubly Robust Estimation of Marginal Cumulative Incidence Curves for Competing Risk Analysis. [PDF]

Stat Med
van Hage P, le Cessie S, van Maaren MC, Putter H, van Geloven N.   +4 more
europepmc   +1 more source

A unified framework of multiply robust estimation approaches for handling incomplete data. [PDF]

Comput Stat Data Anal, 2023
Chen S, Haziza D.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Robust estimation of the latent trait in graded response models. [PDF]

Behav Res Methods
Filonczuk A, Cheng Y.
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Causal Estimands and Multiply Robust Estimation of Mediated-Moderation. [PDF]

Multivariate Behav Res
Liu X, Eddy M, Martinez CR.
europepmc   +1 more source

Robust estimation of dementia prevalence from two-phase surveys with non-responders via propensity score stratification. [PDF]

BMC Med Res Methodol, 2023
Shen C, Pei M, Wang X, Zhao Y, Wang L, Tan J, Deng K, Li N.   +7 more
europepmc   +1 more source