FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Effects of continuum of care for maternal health service utilisation on intention to use family planning among pastoralist women of Ethiopia: a robust regression analysis and propensity score matching modelling. [PDF]
BMJ Open, 2023 Alemayehu M +5 more
europepmc +1 more source
Analysis of Women's Representation in Parliament in Indonesia Using Robust Regression Estimation-S
Jurnal PolitikWomen's representation in parliament is a very important issue to study because one of the SDGs goals is gender equality. Women's representation in parliament in Indonesia is still low, only reaching 21.74 percent in 2022. The low representation of women
I Gede Dewangga Jati Suma +1 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Encoder-Decoder Full Residual Deep Networks for Robust Regression and Spatiotemporal Estimation. [PDF]
IEEE Trans Neural Netw Learn Syst, 2021 Li L, Fang Y, Wu J, Wang J, Ge Y.
europepmc +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Scalable and Robust Regression Methods for Phenome-Wide Association Analysis on Large-Scale Biobank Data. [PDF]
Front Genet, 2021 Bi W, Lee S.
europepmc +1 more source
Robust Logistic Regression for Insurance Risk Classification [PDF]
Risk classification is an important part of the actuarial process in Insurance companies. It allows for the underwriting of the best risks, through an appropriate choice of classification variables, and helps set fair premiums in rate-making.
Esteban Flores, José Garrido
core
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source