Results 91 to 100 of about 3,719,972 (302)
Detection of differential depressive symptom patterns in a cohort of perinatal women: an exploratory factor analysis using a robust statistics approach. [PDF]
EClinicalMedicine, 2023 Nieser KJ +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Application of Robust Statistics to Asset Allocation Models
Revstat Statistical Journal, 2007 Many strategies for asset allocation involve the computation of the expected value and the covariance matrix of the returns of financial instruments.
Roy E. Welsch , Xinfeng Zhou
doaj +1 more source
Hyperspectral imaging and robust statistics in non-melanoma skin cancer analysis. [PDF]
Biomed Opt Express, 2021 Courtenay LA +13 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
robustlmm: An R Package for Robust Estimation of Linear Mixed-Effects Models
Journal of Statistical Software, 2016 As any real-life data, data modeled by linear mixed-effects models often contain outliers or other contamination. Even little contamination can drive the classic estimates far away from what they would be without the contamination.
Manuel Koller
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Robust Nonparametric Early Stopping in Tree Ensembles via IQR-Scale Change-Point Detection
MathematicsTree ensembles—Random Forests (RFs) and Gradient Boosting Machines (GBMs)—often stabilize before all trees are evaluated. We study early stopping as a nonparametric change-point problem on prediction increments.
Sooyoung Jang, Changbeom Choi
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source