Results 131 to 140 of about 1,977,172 (267)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Robust Statistics for GNSS Positioning under Harsh Conditions: A Useful Tool? [PDF]
Sensors (Basel), 2019 Medina D, Li H, Vilà-Valls J, Closas P.
europepmc +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Fréchet and robust statistics [PDF]
, 2006 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Analysis of the spatial organization of molecules with robust statistics. [PDF]
PLoS One, 2013 Lagache T +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Predictive Models in Diagnosis of Alzheimer’s Disease from EEG
Acta Polytechnica, 2013 The fluctuation of an EEG signal is a useful symptom of EEG quasi-stationarity. Linear predictive models of three types and their prediction error are studied via traditional and robust measures.
Lucie Tylova +2 more
doaj
A robust statistics driven volume-scalable active contour for segmenting anatomical structures in volumetric medical images with complex conditions. [PDF]
Biomed Eng Online, 2016 Wang K, Ma C.
europepmc +1 more source